Aims: Glucose evoked changes in profibrotic transforming growth factor-beta1 (TGFs1), increase connexin hemichannel mediated ATP release kidney proximal tubule cells. With linked to inflammation, we evaluated the efficacy of blocker Peptide 5 negating induced inflammatory cytokine secretion cells.
Methods: Primary human tubular epithelial cells (hPTECs), and immortalised (HK2) were treated w...