Using 12-year longitudinal data from deceased participants of the Berlin Aging Study (N = 414; age 70-103 years, at first occasion; M = 87 years, SD = 8.13), the authors examined whether and how old and very old individuals exhibit terminal decline in reported life satisfaction at the end of life. Relative to age-related decline, mortality-related decline (i.e., distance-to-death) accounted for...

Although the alternative oxidase (AOX) has been proposed to play a role in fruit development, the function of AOX in fruit ripening is unclear. To gain further insight into the role of AOX in tomato fruit ripening, transgenic tomato plants 35S-AOX1a and 35S-AOX-RNAi were generated. Tomato plants with reduced LeAOX levels exhibited retarded ripening; reduced carotenoids, respiration, and ethylen...

BACKGROUND Deciding whether to treat postmenopausal women suffering from climacteric symptoms with Continuous Combined Hormone Replacement Therapy (CCHRT) has become increasingly difficult after the release of the Women's Health Initiative results. As a result, development of alternatives to CCHRT is required. Tibolone, which is a synthetic steroid that has estrogenic, progestogenic and androge...

OBJECTIVE To determine the safety and efficacy of a transdermal nanostructured formulation of progesterone (10%) combined with estriol (0.1%) + estradiol (0.25%) for relieving postmenopausal symptoms. METHODS A total of 66 postmenopausal Brazilian women with climacteric symptoms of natural menopause received transdermal nanostructured formulations of progesterone and estrogens in the forearm ...

Fatty acids and amino acids serve as ester precursors, in addition to lipoxyaenase (LOX; EC 1.13.11.12), alcohol dehydrogenase (ADH; EC 1.1.1.1) and alcohol o-acyltransferase (AAT; EC 2.3.1.84) activities, were assessed during maturation of climacteric and nonclimacteric muskmelons. The results showed that the levels of the main fatty acids related to aroma formation containing oleic acid, lino...

A good deal of data are available on the bowel habits of pre-climacteric females during menstruation. Few studies have examined the same subject in females of climacteric age but who are still menstruating, so the present study was undertaken to examine the bowel habits in menstruating females in this age group. Subjects (n = 246) were residents of a city in northern Japan, aged from 45 to 55 y...

The purpose of this study was to translate the self-efficacy for appropriate medication use scale into Thai, and then examine the validity and reliability of this version of the questionnaire. Responses to the 13-item Thai version of the selfefficacy for appropriate medication use scale (SEAMS) were collected from 100 Thai with post-MI. None of the 13 items violated any assumption for factor an...

Mortality-related processes are known to modulate late-life change in cognitive abilities, but it is an open question whether and how precipitous declines with impending death generalize to other domains of functioning. We investigated this notion by using 13-year longitudinal data from now-deceased participants in the Berlin Aging Study (N = 439; 70-103 years at first occasion; M = 87 years). ...