BACKGROUND Clear cell odontogenic carcinoma is a rare odontogenic tumor occurring in the anterior region of the mandible in 5th-7th decades and shows a female preponderance. It is potentially aggressive, capable of frequent recurrences and loco-regional and distant metastases. CASE PRESENTATION A 45-year-old woman presented with a radiolucent left mandibular swelling associated with loss of t...

OBJECTIVE Primary extragonadal germ cell tumors are rare and their histogenetic origin is not clear. We describe two cases presenting as primary retroperitoneal germ cell tumors without clinical evidence of testicular tumor. METHODS A 21 and 18 years-old patients presented retroperitoneal choriocarcinoma and yolk sac tumor, respectively. In both cases, testicular palpation was not suspicious ...

A case of renal cell carcinoma, found after skin metastasis is presented. A 76-year-old woman came to our hospital complaining of two painless subcutaneous tumors in her left chest. Histopathological diagnosis was clear cell carcinoma. She underwent left nephrectomy and histopathological findings revealed renal cell carcinoma, alveolar type, clear cell subtype, grade 1. Lung metastasis was prov...

We read the publication on “Serum tissue factor (TF) as a biomarker for renal clear cell carcinoma”. Silva et al. noted that “TF appears to be a useful serum marker for the presence of clear cell RCC (1)”. Indeed, to conclude that TF is an important biomarker, there should be a complete evaluation on this diagnostic test. Sensitivity and specificity should be studied. Also, some confounding med...

testicular germ cell tumor (tgct) is the most solid tumor in 20-40 years old man. tgct account for 95% of testicular tumors and represent a unique type of human cancer from several different perspectives. tgct arise by transformation of germ cells. the transformed germ cells exhibit ploripotentially to differentiate into embryonic. extra-embryonic, and somatic tissue types, and are highly sensi...

a case is reported with clear cell sarcoma (ccs) of the hand. early diagnosis of clear cell sarcoma is always difficult due to its slow growing nature, benign clinical appearance, lack of pigmentation in most cases, and relatively young age of patients which make it to clinically appear as a benign soft tissue tumor. we report a case of clear cell sarcoma of hand in a 56 year old male with a no...