Let $D$ be a finite simple digraph with vertex set $V(D)$ and arcset $A(D)$. A twin signed total Roman dominating function (TSTRDF) on thedigraph $D$ is a function $f:V(D)rightarrow{-1,1,2}$ satisfyingthe conditions that (i) $sum_{xin N^-(v)}f(x)ge 1$ and$sum_{xin N^+(v)}f(x)ge 1$ for each $vin V(D)$, where $N^-(v)$(resp. $N^+(v)$) consists of all in-neighbors (resp.out-neighbors) of $v$, and (...

Histone deacetylase inhibitors (HDACi) suppress cancer cell growth, inflammation, and bone resorption. The aim of this study was to determine the effect of inhibitors of different HDAC classes on human osteoclast activity in vitro. Human osteoclasts generated from blood mononuclear cells stimulated with receptor activator of nuclear factor kappa B (RANK) ligand were treated with a novel compoun...

A collection of 17 monoclonal antibodies elicited against the light-harvesting chlorophyll a/b protein complex which serves photosystem II (LHC-II) of Pisum sativum shows six classes of binding specificity. Antibodies of two of the classes recognize a single polypeptide (the 28- or the 26- kD polypeptides), thereby suggesting that the two proteins are not derived from a common precursor. Other ...

Case Description- An eleven-year-old Golden retriever male dog (dog I) and a four-year-old neutered Toy Terrier (dog II) were referred to Small Animal Clinic. Dog I was suffered from   partial loss of vision and engorgement of episcleral vessels of his right eye and dog II was blind. Intraocular pressure (IOP) of right eye was 37.8 mmHg in dog  I  and 34.5 and 31.6 mmHg in the right and left...

Amphibia have two classes of olfactory receptors (ORs), class I (fish-like receptors) and class II (mammalian-like receptors). These two receptor classes correspond to the two classes identified in other vertebrates, and amphibians thus provide a unique opportunity to compare olfactory receptors of both classes in one animal species, without the constraints of evolutionary distance between diff...