A short synthesis of the biologically active sesquiterpene natural product (+)-aphanamol I in both racemic and enantiopure forms is reported. Key steps include: a catalytic enantioselective conjugate addition, an oxidative radical cyclization, and a ring-expanding Claisen rearrangement.

A stereocontrolled synthesis of the core of eunicellin is described featuring a Claisen rearrangement and a diastereoselective organocatalytic Diels-Alder reaction as the key steps.

The underlying stereochemically complex and densely functionalized scaffold of the B-seco limonoids was synthesized employing an Ireland-Claisen rearrangement as key transformation.

Wittig olefination-Claisen rearrangement protocol was applied to obtain 3-allyl oxindole. This oxindole was then converted to (±)-coerulescine and (±)-horsfiline.

The theory of contrail formation for fuel cells is derived. It a variant the well-known Schmidt-Appleman theory. factor or G-factor much larger than jet engines, such that condensation exhaust water vapour can happen even at Earth’s surface in sufficiently cold (a few degrees above zero) weather. Contrail from will occur frequently lower troposphere and unavoidable below moderate temperature li...

Introduction We have all heard the old joke of school being all about the three “R’s”, Reading ‘Ritin and ‘Rithmatik, but because of increasing class sizes and reported lack of instruction time, writing has been passed over for the more “important” subjects. The advent of computers and the increasing ease of word processing have given teachers the ultimate excuse, but most beginning composition...

substituted naphthofurans and naphthopyrans were constructed at high temperature from allyl or propargyl naphthyl ethers via claisen rearrangement in moderate to good yields. also, substituted (trimethylsilyl)-naphthofurans were synthesized from the corresponding naphtofurans.

γ,δ-Unsaturated amino acids are the backbone of various natural products and pharmaceuticals, while quaternary α-amino also powerful enzyme inhibitors, both very important compounds in bioorganic chemistry. A highly efficient synthesis γ,δ-unsaturated esters utilizing tandem umpolung/Claisen rearrangement for α-iminoallyl was developed. This method has a wide range substrates taking account Ham...

SLs (sphingolipids) are composed of fatty acids and a polar head group derived from L-serine. SLs are essential components of all eukaryotic and many prokaryotic membranes but S1P (sphingosine 1-phosphate) is also a potent signalling molecule. Recent efforts have sought to inventory the large and chemically complex family of SLs (LIPID MAPS Consortium). Detailed understanding of SL metabolism m...