Introduction: One of the complications using implants in patients is peri-implantitis which occurs due to invasion Prevotella intermedia bacteria. Therefore, we need an agent that can play a role inhibiting growth these bacteria, including lime juice. Lime (Citrus aurantifolia) herbal plant often used by community traditional medicine because it contains antibacterial compounds. The purpose thi...

HT048 is a combination composed of Crataegus pinnatifida leaf and Citrus unshiu peel extracts. This study aimed to investigate potential anti-obesity effect of the combination. The 3T3-L1 adipocytes were treated with different doses of HT048 and triglyceride accumulation, glycerol release and adipogenesis-related genes were analyzed. For in vivo study, male Sprague Dawley rats were divided acco...