We present a preliminary first-pass dynamic model for delivery of drug compounds to the lungs and heart. We use a compartmental mass balance approach to develop a system of nonlinear differential equations for mass accumulated in the heart as a result of intravenous injection. We discuss sensitivity analysis as well as methodology for minimizing mass in the heart while maximizing mass delivered...

Background. Primo vascular system is a new anatomical structure whose research results have reported the possibility of a new circulatory system similar to the blood vascular system and cells. Electrophysiology, which measures and analyzes bioelectrical signals tissues and cells, is an important research area for investigating the function of tissues and cells. The bioelectrical study of the pr...

Circulation plays an important rule in gas exchange. Therefore, there is an interaction between circulation and gas exchange. To understand the dynamic effect of these two physiological systems, a computer simulation model of hemodynamics and gas exchange is established in this work. This model includes two physiological systems, namely the respiratory and circulatory systems. It consists of fi...

The immune system of cephalopods remains poorly understood. The aim of this study was to determine the specific activity of immune enzymes in epithelial barriers, circulatory and digestive systems of the common cuttlefish Sepia officinalis. Three enzyme groups with putative functions in immunity were investigated: phenoloxidases (POs), lysozymes and protease inhibitors (PIs). Consistent with a ...

Students’ learning activities that are hard to recognite by students give an impact on enthusiastic about learning. It is necessary adjust a variety of learning, increase the cognitive skill such as Project Based Learning model. This study aims determine effect model 8th grade human circulatory system topic. The research method used Quasi Experiment with Non-equivalent Post Test Only Control Gr...

BACKGROUND The extracorporeal membrane oxygenation (ECMO) has been used in the neonatal and childhood periods with excellent results. The adult experience has been modest with inferior immediate results. The intermediate survival, however, has been promising. We have been using the extracorporeal membrane oxygenation for temporary mechanical circulatory support of adults that present with acute...