miRNAs (microRNAs) participate in many diseases including cardiovascular disease. In contrast with our original hypothesis, miRNAs exist in circulating blood and are relatively stable due to binding with other materials. The aim of the present translational study is to establish a method of determining the absolute amount of an miRNA in blood and to determine the potential applications of circu...

Selected circulating microRNAs (miRNAs) have been suggested for non-invasive screening of non-small cell lung cancer (NSCLC), however the numerous proposed miRNA signatures are inconsistent. Aiming to identify miRNAs suitable specifically for stage I-II NSCLC screening in serum/plasma samples, we searched the databases "Pubmed", "Medline", "Scopus", "Embase" and "WOS" and systematically reviewe...

This study demonstrates a passive mode-locked erbium-doped fiber laser with graphene nanoplatelet-saturable absorber (GNP-SA) that generates ultrashort pulses within femtosecond pulse duration. The GNP-SA is fabricated via direct transfer approach by mechanically exfoliated on ferrule. Its characteristics include 0.8% modulation depth, 8.7 MW/cm2 saturation fluence, and 36.8% absorbance. qualit...

abstract background and aims: influenza a(h5n1) viruses  circulating in animals might evolve and acquire the ability to spread from  human to human and thus start a pandemic. hemagglutinin (ha) has been shown to play a major role in binding of influenza virus to its target cell and the main neutralizing antibody responses elicit against this region. recent studies have shown that glycosylation ...

background and aims: influenza a(h5n1) viruses  circulating in animals might evolve and acquire the ability to spread from  human to human and thus start a pandemic. hemagglutinin (ha) has been shown to play a major role in binding of influenza virus to its target cell and the main neutralizing antibody responses elicit against this region. recent studies have shown that glycosylation of ha is ...

Due to the single phase characteristic of individual arms Modular Multilevel Converter (MMC) topology, difference between instantaneous AC and DC side power must be buffered in module capacitors. This results large capacitors compromising density cost MMC. In this paper, a multi-objective optimization scheme is formulated that aims at reducing required capacitance semiconductor losses same time...

The purpose of this study are to understand the legal protection halal product label as role and authority Halal Product Assurance Agency (BPJPH) according Law No.33 2014 advantages disadvantages Guarantee after enactment No. 11 2020 concerning Job Creation which has changed some provisions JPH Law. That no. 33 requires all products circulating in Indonesia be certified. presence Number changes...

The Modular Multilevel Converter is a good alternative for high power, medium voltage drive applications due to its modularity and scalability. However, the control complex typically involves several highly-coupled circulating current feedback loops implemented using Single-Input Single-Output design tools. Additionally, each has many different frequency components electrical sequences increase...

Hemodynamic forces tune the arrest, adhesion and extravasation of circulating tumor cells Gautier Follain, Naël Osmani, Sofia Azevedo, Guillaume Allio, Luc Mercier , Matthia A. Karreman, Gergely Solecki, Nina Fekonja, Claudia Hille, Vincent Chabannes, Guillaume Dollé, Thibaut Metivet, Christophe Prudhomme, Bernhard Ruthensteiner, André Kemmling, Susanne Siemonsen, Tanja Schneider, Jens Fiehler,...