Childhood Hepatitis B virus (HBV) infection causes both medical and public health challenges. Infants who acquire HBV parentally have up to 90% risk of developing chronic HBV infection. It is now estimated that approximately 10% of worldwide cancers are attributable to viral infection, with the vast majority (>85 %) occurring in the developing world. In this distribution, elevated rate and prev...

Background: Nursing practice has to contribute to evidence pointing out why there is a need for more nurse-designed randomized control trials (RCTs) focusing on evidence-based practice (EBP). How far this EBP has progressed in different health aspects is usually established by systematic reviews of RCTs. Nurse-led RCTs exist but no study has addressed the essentials of nursing care. Aim: The ai...

Currently, demographic trends, at a global level, are characterized by an increase in the older age group. Associated to advanced age, older people are more prone to chronic diseases, and they are confronted with the need to adhere to an often complex medication regimen. Non-adherence has a negative impact at individual and global level. The purpose of this systematic review was answering the q...

Re-injury to a recently rehabilitated or operated knee is a common occurrence that can result in significant loss of function. Knee stability measures have been used to diagnose and assess knee stability before and after rehabilitation interventions. Here, we systematically review the literature and evaluate the different anterior-posterior and rotational knee stability measures currently in us...

Background: Medication error is the most common adverse event for hospitalised children and can lead to significant harm. Despite decades of research and implementation of a number of initiatives, the error rates continue to rise, particularly those associated with administration. Objectives: The objective of this literature review is to explore the factors involving nurses, families and health...

Objective: To provide evidence regarding the therapeutic effects of exercise on subjects with patellofemoral-pain syndrome (PFPS). Data Sources: Evidence was compiled with data located using the Medline, CINAHL, and SPORTDiscus databases from 1985 to 2004 using the key words patellofemoral pain syndrome, exercise, rehabilitation, and strength. Study Selection: The literature review examined int...

Objective/Background: Heart Failure (HF) places substantial burden on patients, families, communities, and care systems. Patients who suffer from HF often experience a decline in health resulting in recurrent hospitalizations and debilitating symptoms including breathing problems, fluid retention, and chronic fatigue. HF is the most common cause of repeat hospitalizations in the Medicare progra...

Alzheimer disease is 1 of 5 leading causes of death in persons older than 65 years. The term suffering is used in all disciplines and a variety of contexts with no clear universal definition. Identifying dimensions and qualities (dimensional analysis) of the concept of suffering will assist in better understanding the concept and being able to apply it to science and practice. The objectives of...