DNA damage (determined by the Comet Assay) and the occurrence of deformed nuclei were measured as endpoints of genotoxicity in male gonad cells of the marine mussel (Perna viridis). Upon exposure of the organism to varying concentrations of extracts of smoked and non-smoked cigar tobacco over a period of 16 days, DNA damage was found to be highest in marine mussels exposed to extracts of smoked...

In the dilatonic domain wall model, we study the Schwarzschild black hole as a solution to the Kaluza-Klein (KK) zero mode effective action which is equivalent to the Brans-Dicke (BD) model with a potential. This can describe the large Randall-Sundrum (RS) black hole whose horizon is to be the intersection of the black cigar with the brane. The black cigar located far from the AdS 5-horizon is ...

Carboxyhaemoglobin (COHb) levels were studied in 11 249 men. The distribution among the 2613 men who smoked cigarettes was well separated from that in 6641 non-smokers (including ex-smokers). The distribution for 2005 cigar and pipe smokers was intermediate, though some of the highest COHb levels occurred in cigar smokers. Using a COHb cut-off level of 2%, 81% of cigarette smokers, 35% of cigar...

BACKGROUND In the 1990s, youth use of alternative tobacco products including cigars, bidis, and kreteks increased. This article discusses the prevalence of youth use of cigars, bidis, and kreteks, and characteristics of users. METHODS The Cigar Use Reasons Evaluation (CURE)-a questionnaire assessing alternative tobacco use and associated attitudes and behaviors-was administered to middle and ...

2012;379:1173. 26 Swanson JM. UK Biobank and selection bias. Lancet 2012; 380:110. 27 Davey Smith G, Lawlor DA, Harbord R et al. Clustered environments and randomized genes: a fundamental distinction between conventional and genetic epidemiology. PLoS Med 2007;4:e352. 28 Mayer-Schonberger V, Cukier K. Big Data. London: John Murray, 2013. 29 Mills H. Analytics: turning data into dollars. Forward...

Tobacco smoking is associated with an increased risk of cancer in a number of organs, including bladder and lung. Tobacco smoke contains at least 50 known chemical carcinogens that exert their biological effects through their covalent binding to cellular DNA. Examining human DNA for the presence of altered nucleotides is a means of monitoring exposure to genotoxic chemicals. DNA isolated from 7...