Carcinogenic heterocyclic amines are activated by N-acetyltransferase (NAT) enzymes, encoded by NAT1 and NAT2, to genotoxic compounds that can form DNA adducts in the colon epithelium. We have examined the relation of polymorphisms in the genes coding for both enzymes to risk of colorectal cancer and the gene-environment interaction with red meat intake among participants in the prospective Phy...

The properties of Na+-dependent L-alanine transport in human erythrocytes were investigated using K+ as the Na+ substitute. Initial rates of Na+-dependent L-alanine uptake (0.2mM extracellular amino acid) for erythrocytes from 22 donors ranged from 40 to 180pmol/litre of cells per h at 370C. Amino acid uptake over the concentration range 0.1-8mm was consistent with a single saturable component ...

Several semantic and syntactic distinctions, which have largely been neglected in the Vietnamese linguistic literature, are drawn together in this paper in a comparative context with other better-studied languages in order to indicate that Inner Aspect is projected within the VP shell and independently of the projection of Outer Aspect – a structural proposal originally advanced by Travis (2010...

KLOCKE, ROBERT A., KAJSA K. ANDERRSON.HAROLD H. ROT. MAN, AND ROBERT E. FORSTER. Permeability of human ery throcy tes to ammonia and weak acids. Am. J. Physiol. 222(3): 1004-1013. 1972.We have developed a continuous-flow rapid-reaction apparatus, using a glass pH electrode, capable of measuring changes in pH of ho.01 unit as early as 0.01 set after mixing. With this apparatus we have measured t...

The clinical value of measuring concentrations of methylmalonic acid in serum (S-MMA) as an aid in the diagnosis of cobalamin deficiency has recently aroused interest. In 58 healthy subjects, ages 40-68 years, we found a 0.95 reference interval of 0.05-0.37 mumol/L (mean 0.21, SD 0.094). In 33 of the subjects, who were studied further, day-to-day variation (SD) was 0.031 mumol/L. Intake of food...

Dueto theactionofo-quinones formedviapolyphenoloxidase, conserved red clover (Trifolium pratense L.) contains abundant rumen undegradable protein (RUP), but inadequate rumen degradable protein (RDP) fordairy cattle. This studyexaminedhowforagemanagement influences RDP, RUP, crude protein (CP) and fiber fractions in red clover silage and dry matter (DM) yields during the first full production ye...

To evaluate the effects of endurance training in rats on fatty acid metabolism, we measured the uptake and oxidation of palmitate in isolated rat hindquarters as well as the content of fatty acid-binding proteins in the plasma membranes (FABP(PM)) of red and white muscles from 16 trained (T) and 18 untrained (UT) rats. Hindquarters were perfused with 6 mM glucose, 1,800 microM palmitate, and [1...

The present investigation has been carried out to investigate the biological role of four different types of baby-leaf salads and to study their potential as natural sources of antioxidants and antimicrobials against several isolates from important human pathogenic bacteria. Four single types of salads (green lettuce, red lettuce, rucola and watercress) and two mixtures [(1) red lettuce+green l...

We examined fatty acid transporters, transport, and metabolism in hearts and red and white muscles of lean and insulin-resistant (week 6) and type 2 diabetic (week 24) Zucker diabetic fatty (ZDF) rats. Cardiac fatty acid transport was similar in lean and ZDF hearts at week 6 but was reduced at week 24 (-40%) in lean but not ZDF hearts. Red muscle of ZDF rats exhibited an early susceptibility to...