Bu çalışma kurşun asetat (PbA) kaynaklı karaciğer hasarı üzerine chrysinin (CH) etkilerinin araştırılması amacıyla yapıldı. Çalışmada 35 adet Sprague Dawley cinsi erkek rat, her grupta 7 rat olacak şekilde 5 gruba ayrıldı. 1. Grup (Kontrol): Oral yolla serum fizyolojik verildi. 2. (CH grubu): CH (50 mg kg-1 ağırlık gün-1) gün boyunca oral olarak ratlara 3. (PbA PbA (30 kg-1) 30 4. (PbA+CH 25 mg...

No clear data are available on how flavonoids from different chemical groups affect root colonization by arbuscular mycorrhizal fungi (AMF) and whether flavonoids affecting the presymbiotic growth of AMF also affect root colonization by AMF. In the present work, we compared the effect of flavones (chrysin and luteolin) and flavonols (kaempferol, morin, isorhamnetin, and rutin) on root colonizat...

INTRODUCTION It is well known that the presence of Helicobacter pylori in the stomach induces gastritis and causes an immune response. Exposure of gastric epithelial cell lines to this germ induces the secretion of interleukin-8 (IL-8), which is a potent PMN-activating chemotactic cytokine. Interleukin-8 is usually elevated in gastric biopsy samples of patients with H. pylori-associated gastrit...

Phytoestrogens are of interest because of their reported beneficial effects on many human maladies including cancer, neurodegeneration, cardiovascular disease and diabetes. Furthermore, there is a search for compounds with estrogenic activity that can replace estrogen in hormone replacement therapy during menopause, without the undesirable effects of estrogen, such as the elevation of breast ca...

Flavone analogs are natural compounds of the flavonoid class that have a wide range biological activities. The present study aimed to predict, with aid in silico methodologies, oral bioavailability and pharmacokinetic toxicological analyzes for three flavone analogues (apigenin, chrysin luteonlin). revealed good availability, favorable parameters. Virtual Screening performed predict all did not...

The present manuscript reviews the findings of different research studies that evaluate use fungal solid-state (SSF) and submerged culture fermentation (SCF) with agro-industrial residues as substrates to enhance production polyphenols their possible uses food additives. Some (peels, pulps seeds) are an important source phenolic acids (p-coumaric, p-hydroxybenzoic, chlorogenic, cinnamic, feruli...

The radioprotective effects of water-soluble derivate of propolis (WSDP) collected in Croatia, and single flavonoids, caffeic acid, chrysin and naringin in the whole-body irradiated CBA mice were investigated. Irradiation was performed using a gamma-ray source ((60)Co), and absorbed doses were 4 and 9 Gy. The efficiency of test components was evaluated when given intraperitoneally (i.p.) at dos...