pulmonary hypertension (ph) is an important cause of heart failure in chronic obstructive pulmonary disease (copd). the pro brain natriuretic peptide n-terminal (nt-probnp) has been suggested as a noninvasive marker to evaluate ventricular function. however, there is no evidence to support the use of nt-probnp in monitoring the benefits of vasodilators in copd induced ph. thus, we used nt-probn...

chronic granulomatous disease (cgd) is a rare inherited disorder characterized by inability of phagocytes to generate oxygen radicals needed for intracellular killing of phagocytic microorganisms. we report a 2.5-year-old iranian female with multiple liver abscesses. she was admitted in surgical ward because of abdominal pain and fever for one month duration that had no response to conventional...

conclusions in short term, using the self-management program can lead to increased exercise tolerance and decreased dyspnea in patients with copd; thus, this program is recommended as an effective way to improve the functional statuses of these patients. results there was no significant difference between the groups in exercise tolerance at base line; but, they were significantly different at t...

background: several studies have showed an increased prevalence of airflow obstruction in first degree relatives of individuals with chronic obstructive pulmonary disease (copd). considering no specific research had evaluated airway resistance in offspring of patients with severe copd, we utilized a spirometry and a impulse oscillometry (io) to evaluate this population. materials and methods: i...

background & aim: the aim of this clinical trial study was to evaluate sleep quality in patients with chronic lung disease and the role of controlled breathing to improve the quality of sleep. methods & materials: sixty-four patients with chronic lung disease in two group (experimental and control group) enrolled in a 7 weeks. before interventions, the pittsburgh sleep quality index (psqi) and ...

The increasing use of beryllium in a variety of industries continues to be a hazard. New cases are still being reported to the UK Beryllium Case Registry, now numbering 60 in the period 1945-1988. The majority of cases follow inhalation which results in acute beryllium disease (chemical pneumonitis) or more commonly chronic beryllium disease--a granulomatous pneumonitis. Granulomatous skin nodu...

Abstract Hidradenitis suppurativa (HS) is a chronic recurrent debilitating condition. It characterized by abscesses, and can be complicated rupture, scarring sinuses. The management of HS multidisciplinary, involving general lifestyle modification, medical treatment, surgery. A wide range surgical interventions have been described for disease control management. However, strategies are highly v...

background: allergic fungal sinusitis is a non-invasive disease, and accounts for approximately 6-8% of all chronic sinusitis requiring surgical intervention. as the treatment and prognosis of these disorders vary significantly, it is extremely important to recognize allergic fugal sinusitis and differentiate it from chronic sinusitis of bacterial and fungal origin. this prospective study evalu...

Background: There has recently been increasing interest in the role of the human microbiome in disease. Antibiotic use is known to disrupt the intestinal microbial environment and cause acute disease, for example pseudomembranous colitis. This study aimed to investigate the hypothesis that long-term antibiotic use is associated with the development of chronic diseases, i.e., Asthma, Rheumatoid ...

background and aims. pemphigus is a chronic autoimmune and vesiculobollous disease that can affect skin and different mucous membrane surfaces. primary manifestations occur in oral cavity in almost 60% of cases. the purpose of the present study was to evaluate the epidemiology of pemphigus in tehran, iran in a 20-year period. materials and methods. a retrospective study was conducted on the rec...