HYPOTHESIS We designed a study to determine the role of mastoid mucosal biofilm in chronic otitis media (COM). BACKGROUND Biofilm formation has been found in several chronic airway infections. COM is associated with chronic, recalcitrant infection of the mastoid mucosa, and surgery often is required. METHODS COM patients were divided into 2 groups: one with chronic suppurative otitis media ...

Intracranial complications of otitis media are still a condition of risk with a high mortality rate, notwithstanding the significant reduction of such complication with the advent of antibiotics. Although less frequent, chronic cholesteatomatous otitis media is usually associated with the highest risk of complications, given its destructive and invasive potential. These complications may be sub...

Active chronic otitis media is a common condition affecting 0 6%,' of adults in the United Kingdom. Initial management is usually by general practitioners, who annually prescribe systemic and topical antibiotics on at least 178 000 and 73 000 occasions respectively (unpublished observations). Despite this there have been few studies of the efficacy of antibiotics,'-4 and no study has included a...

A 17 year old male presented with seizures, headache, and fever and left chronic suppurative otitis media. A 35 year old male presented with headache, giddiness, vomiting, pain in eyes, diplopia and right chronic suppurative otitis media. Brain imaging in both revealed thrombosis of lateral and sigmoid sinus and also of internal jugular vein on the left and right side respectively. A diagnosis ...