Chronic obstructive lung disease (COPD) is a chronic multisystem disease with a considerable burden. One of its most common complications is pulmonary artery hypertension (PAH). It has been demonstrated that the development of PAH is correlated with decreased quality of life and survival. Different medications have been proposed for the treatment of PAH, among which one can name statins. Howeve...

Bronchoscopy with bronchoalveolar lavage (BAL) is an important research tool for assessing airway inflammation in a variety of inflammatory lung diseases. In chronic obstructive pulmonary disease (COPD), BAL recovery is often low, making analysis of the recovered fluid difficult to interpret. The present authors hypothesised that the degree of emphysema may predict BAL recovery. A total of 20 C...

Dysfunctional protein quality control is emerging as a key pathogenic mechanism for chronic lung diseases. Two major hereditary conformational disorders of the lung, cystic fibrosis and a1-antitrypsin (a1-AT) deficiency, and some familial forms of idiopathic pulmonary fibrosis (IPF) are caused by the expression of mutant and misfolded proteins that disrupt protein homeostasis and drive the onse...

T he readers of the European Respiratory Journal are well aware of the importance of environmental exposures on the incidence and aggravation of several respiratory disorders, including asthma and chronic obstructive pulmonary disease (COPD), leading in some cases to mortality. Almost each month, one or more scientific articles deal with environmental lung diseases or with environmentally induc...

Photobiomodulation is the use of visible and infrared light through emitting diodes - LED without thermal cytotoxic reactions.It was carried out a literature review with this studyto understand photobiomodulation applied to Chronic Obstructive Pulmonary Disease COPD.It survey in January 2023, SciELO, Lilacs, Pubmed, Medline Google Scholar databases. With descriptors “Low-level therapy” AND “Chr...

BACKGROUND Inflammation in the airways and lung parenchyma underlies fixed airway obstruction in chronic obstructive pulmonary disease. The exact role of smoking as promoting factor of inflammation in chronic obstructive pulmonary disease is not clear, partly because studies often do not distinguish between current and ex-smokers. METHODS We investigated airway inflammation in sputum and bron...

Over the last decade, deep learning (DL) has contributed to a paradigm shift in computer vision and image recognition creating widespread opportunities of using artificial intelligence research as well industrial applications. DL been extensively studied medical imaging applications, including those related pulmonary diseases. Chronic obstructive disease, asthma, lung cancer, pneumonia, and, mo...

Osteoporosis in chronic obstructive pulmonary disease. A.A. Ionescu, E. Schoon. #ERS Journals Ltd 2003. ABSTRACT: Osteoporosis is one of the systemic effects associated with chronic obstructive pulmonary disease (COPD). Potential risk factors of osteoporosis may be due to the lifestyle, genetics, treatment with corticosteroids, endocrine abnormalities or the impairment of the body composition a...