Headache is one of the most common medical complaints of humankind that occurs in all age groups and is the seventh leading reason for medical office visits. The most common cause of chronic headache is migraine that affects an estimated 10-15% of the population. However, many drugs are useful for treatment of headache, current conventional medications have many side effects. Therapeutic trials...

Chronic migraine is a disabling condition which affects a considerable proportion of patients. Several risk factors and lifestyle habits contribute to the transformation of migraine into a chronic form. Behavioral treatments, including relaxation, biofeedback, and cognitive behavioral therapy reduce the risk of episodic into chronic migraine transformation, thus restraining the headache-related...

Headache is an almost ubiquitous human experience. In addition, it is a major contemporary health problem about which most clinicians are poorly informed. Over two-thirds of the population report a history of headache, with 28% fulfilling criteria for a diagnosis of migraine and 38% for tension-type headache.' Patients come to medical attention either because of diagnostic doubt (is it a brain ...

The entity of chronic daily headache (CDH) is well documented, but is not included in the current classification. We divided patients with CDH into groups with and without migrainous features. This division resulted in clearly distinguishable syndromes of daily migrainous headaches (DMH) and daily tension-type headaches (DTH). Family history of headaches was more common in patients with DMH. Pa...

About one fifth of the patients seen by a general neurologist in the UK will present with headache; the majority have a chronic or stable syndrome (mostly migraine and chronic daily headache). Most patients are assessed in the relative peace and calm of the outpatient clinic, and their management is dealt with elsewhere in this supplement. A small proportion of headache patients will present ac...