نتایج جستجو برای: chromosome type

تعداد نتایج: 1443937  

Journal: :Diabetes 2001
T R Merriman H J Cordell I A Eaves P A Danoy F Coraddu R Barber F Cucca S Broadley S Sawcer A Compston P Wordsworth J Shatford S Laval J Jirholt R Holmdahl A N Theofilopoulos D H Kono J Tuomilehto E Tuomilehto-Wolf R Buzzetti M G Marrosu D E Undlien K S Rønningen C Ionesco-Tirgoviste J P Shield F Pociot J Nerup C O Jacob C Polychronakos S C Bain J A Todd

Some immune system disorders, such as type 1 diabetes, multiple sclerosis (MS), and rheumatoid arthritis (RA), share common features: the presence of autoantibodies and self-reactive T-cells, and a genetic association with the major histocompatibility complex. We have previously published evidence, from 1,708 families, for linkage and association of a haplotype of three markers in the D18S487 r...

2017

Structural chromosome aberrations or chromosome mutations represent apart from aneuploidies the most frequent pathologic findings in applied chromosome diagnostics. But they also occur as combinations of both types as in unstable rearrangements or in chaotic karyotypes of early stages of embryonic development. Depending on the indication for chromosome analysis—child with developmental retardat...

Journal: :Evolution; international journal of organic evolution 2001
F Perfectti J H Werren

A centric fragment was generated during the introgression of a chromosome region from Nasonia giraulti into N. vitripennis. This neo B chromosome carries the N. giraulti or 123+ gene for wild-type eye color. Using this phenotypic effect, the transmission of this chromosome was analyzed. The supernumerary chromosome showed less than Mendelian segregation rate in meiosis and some mitotic instabil...

2004
T. KOP LESŁAW PRZYWARA ELŻBIETA KUTA JOANNA KŁOS

In a study of Plagiomnium undulatum from Poland, variability in karyotype formula and chromosome set length contrasted with high uniformity of chromosome number. Haploid chromosome number n = 6 was counted in 215 of 216 metaphases of plants originating from five populations, and n = 7 (6 + 1m) in one cell. The chromosomes were examined and ranked by total and relative length and arm ratio. The ...

Journal: :molecular biology research communications 2013
mozhgan sedigh-ardekani iraj saadat mostafa saadat

propranolol (pl), a non-selective beta-blocker, is a cardiovascular drug widely used to treat hypertension. the present study was concerned with assessing the cytogenetic effects of this drug on chinese hamster ovary (cho) cell line. mtt assay was then carried out to determine the cytotoxicity index (ic50) of the drug. the ic50 value of pl was 0.43±0.02 mm. to investigate the clastogenic effect...

ژورنال: :مجله گیاهشناسی ایران 1999
سید رضا صفوی

مشاهدات کروموزومی 16 نمونه متعلق به 12 گونه گزارش می شود. شش گونه از گونه های مذکور برای این اولین بار شمارش کروموزومی شده اند. همچنین رفتار کروموزومی در تقسیم میتوز گونه ها مورد توجه قرار گرفته است.

Journal: :Genetics 2011
John S Choy Rachel Acuña Wei-Chun Au Munira A Basrai

Hypoacetylated H4 is present at regional centromeres; however, its role in kinetochore function is poorly understood. We characterized H4 acetylation at point centromeres in Saccharomyces cerevisiae and determined the consequences of altered H4 acetylation on chromosome segregation. We observed low levels of tetra-acetylated and K16 acetylated histone H4 (H4K16Ac) at centromeres. Low levels of ...

Journal: :Genetics 1986
D D Perkins R L Metzenberg N B Raju E U Selker E G Barry

In translocation OY321 of Neurospora crassa, the nucleolus organizer is divided into two segments, a proximal portion located interstitially in one interchange chromosome, and a distal portion now located terminally on another chromosome, linkage group I. In crosses of Translocation X Translocation, exceptional progeny are recovered nonselectively in which the chromosome sequence has apparently...

Journal: :Genetics 1980
L Mori A L Perondini

It was previously assumed that the X-linked recessive mutation, sepia, induced errors in X-chromosome elimination during early embryogenesis of Sciara ocellaris. The results obtained in the present analysis corroborate this assumption and permit a further classification of the type of error this mutation induces. Among 85,244 individuals analyzed, three kinds of aberrant flies were identified: ...

Journal: :Genetics 1976
W Kunz Schäfer

The number of rRNA cistrons is measured by filter saturation hybridization in different stocks of D. hydei, where the wild-type X chromosome has one nucleolus organizer (NO) and wild-type Y has two separated NO's. XX/Y females having no X chromosomal NO show an rDNA content exceeding that of a Y chromosome. An even greater increase in the rRNA cistron number is measured in two translocation sto...

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