نتایج جستجو برای: choroidal melanoma

تعداد نتایج: 61480  

2010
Eleni Loukianou Dimitrios Brouzas Eleni Georgopoulou Chrysanthi Koutsandrea Michael Apostolopoulos

PURPOSE To evaluate the safety and efficacy of intravitreal injections of bevacizumab (Avastin((R))) as a treatment option for radiation maculopathy secondary to proton beam radiotherapy for choroidal melanoma. CASE A 61-year-old woman presented with a gradual decrease in left eye visual acuity (VA) 29 months after proton beam radiotherapy for choroidal melanoma. On presentation, her best-cor...

2008
Chryssanthi Koutsandrea Marilita M Moschos Michael Dimissianos Gerasimos Georgopoulos Ioannnis Ladas Michael Apostolopoulos

PURPOSE To investigate tumor thickness and location, the interval of time between treatment for choroidal melanoma (proton beam irradiation or enucleation) and diagnosis of metastatic disease, and rates and sites of metastasis. DESIGN Retrospective, interventional, noncomparative case series. METHODS Follow-up of 152 patients with primary choroidal melanoma, between 1992 and 2006 (14 years)...

Journal: :Investigative ophthalmology & visual science 2000
F Mouriaux C A Maurage P Labalette B Sablonnière F Malecaze J M Darbon

PURPOSE Recent studies have demonstrated the close link between oncogenesis and cell cycle machinery. Cyclin-dependent kinase inhibitory proteins (CKIs) have been shown to play a critical role in the regulation of cell cycle progression. Alteration of CKI levels and/or functions could be implicated in cell transformation. The three CKIs-p16, p21, and p27-were investigated in human uveal melanom...

Journal: :British Journal of Ophthalmology 1997

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