نتایج جستجو برای: cholinergic system

تعداد نتایج: 2245484  

2015
Léa Milan Gilles Courtand Laura Cardoit Frédérique Masmejean Grégory Barrière Jean-René Cazalets Maurice Garret Sandrine S. Bertrand Cedric Raoul

Large cholinergic synaptic terminals known as C-boutons densely innervate the soma and proximal dendrites of motoneurons that are prone to neurodegeneration in amyotrophic lateral sclerosis (ALS). Studies using the Cu/Zn-superoxide dismutase (SOD1) mouse model of ALS have generated conflicting data regarding C-bouton alterations exhibited during ALS pathogenesis. In the present work, a longitud...

2014
Liliana Purón-Sierra María Isabel Miranda

The ability of acetylcholine (ACh) to alter specific functional properties of the cortex endows the cholinergic system with an important modulatory role in memory formation. For example, an increase in ACh release occurs during novel stimulus processing, indicating that ACh activity is critical during early stages of memory processing. During novel taste presentation, there is an increase in AC...

Journal: :Clinical science 2008
Ana Martínez-López de Castro Susana Nieto-Cerón Pons-Castillo Aurelio Lilian Galbis-Martínez Juan Latour-Pérez Juan Torres-Lanzas Isabel Tovar-Zapata Pedro Martínez-Hernández José Neptuno Rodríguez-López Juan Cabezas-Herrera

In non-neuronal contexts, ACh (acetylcholine) is thought to be involved in the regulation of vital cell functions, such as proliferation, differentiation, apoptosis and cell-cell interaction. In airways, most cells express the non-neuronal cholinergic system, each containing a specific set of components required for synthesis, signal transduction and ACh hydrolysis. The aim of the present study...

2006
Niladri Basu Anton M. Scheuhammer Kirsti Rouvinen-Watt Nicole Grochowina Kate Klenavic R. Douglas Evans Hing Man Chan Laurie H.M. Chan

The effects of methylmercury (MeHg) on components of the cholinergic system were evaluated in captive mink (Mustela vison). Cholinergic parameters were measured in brain regions (occipital cortex, cerebellum, brain stem, basal ganglia) and blood (whole blood, plasma, serum) following an 89 d exposure to MeHg at dietary concentrations of 0, 0.1, 0.5, 1, and 2 ppm (n = 12 animals per treatment). ...

Journal: :Journal of neurophysiology 2010
Mia Ericson Michelle A Sama Hermes H Yeh

The septohippocampal system has been implicated in the cognitive deficits associated with ethanol consumption, but the cellular basis of ethanol action awaits full elucidation. In the medial septum/diagonal band of Broca (MS/DB), a muscarinic tone, reflective of firing activity of resident cholinergic neurons, regulates that of their noncholinergic, putatively GABAergic, counterparts. Here we t...

Journal: :iranian biomedical journal 0
بنفشه اسمعیل زاده banafshe esmaeilzade ملیحه نوبخت maliheh nobakht محمدتقی جغتایی mohammad taghi joghataei ناهید رهبر روشندل nahid rahbar roshandel هما رسولی homa rasouli علی صمدی کوچک سرایی ali samadi kuchaksaraei سید محمد حسینی

background: alzheimer’s disease (ad) is characterized by progressive neuronal loss in hippocamp. epidermal neural crest stem cells (epi-ncsc) can differentiate into neurons, astrocytes and oligodendrocytes. the purpose of this study was to evaluate the effects of transplanting epi-ncsc into ad rat model. methods: two weeks after induction of ad by injection of amyloid-β 1-40 into ca1 area of ra...

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