The biochemical and hormonal data in patients with adrenal incidentalomas were evaluated to compare the differences between adrenal adenomas and other benign lesions and to find the relationship between metabolic parameters and adrenal hormones. Ninety two patients (29men, age 20-90 years) with incidentally discovered unilateral or bilateral adrenal masses detected on CT were included in this s...

M ultifocal angiopathy associated with cannabis consumption is an uncommon cause of ischemic stroke in young individuals. The main radiological characteristics include the presence of multifocal intracranial stenosis and the reversibility of vasoconstriction after cannabis withdrawal. 1–3 Cannabis use has been linked recently to other arterial complications, including myocardial infarction (str...

BACKGROUND Prevention of chronic kidney disease (CKD) is a major public health issue. Although several studies have been performed on the association between alcohol consumption and CKD or renal function, it remains controversial. Numerous genetic polymorphisms have been reported to be associated with CKD and kidney function. Mitochondrial DNA cytosine/adenine (Mt5178 C/A) polymorphism is assoc...

326 ABSTRACT: With a prevalence rate of approximately 1 case in 500 people, heterozygous familial hypercholesterolemia is one of the most common genetic disorders encountered in clinical practice. Affected individuals have an impaired hepatic clearance of low-density lipoprotein particles and are thus predisposed to hyper cholesterolemia, with a consequent twentyfold increased risk of premature...

A micromethod adapted for automated determinations was used to measure basal plasma levels of homocyst(e)ine [H(e)]. These levels included the sum of free and bound forms of homocysteine, its disulfide oxidation product, homocystine, and the homocysteine-cysteine-mixed disulfide. Two groups of subjects were studied: apparently healthy individuals (n = 103) and patients with peripheral arterial ...

The importance of heredity in determining the cholesterol, lipoprotein, and plasma protein levels has received insufficient attention. All of these have a greater concentration in the blood of short-fat (mesomorphic), castrate, male, miniature pigs than in long-lean (ectomorphic) animals. These differences seem to persist even when weight changes and growth are rapid. We believe that some of th...

The cardiovascular pathologies are the most common causes of death in the elderly patient. To single out the main risk factors in order to effectively prevent the onset of the disease, the authors experimented a special computerized tool, the neural network, that works out a mathematical relation that can obtain certain data (defined as output) as a function of other data (defined as input). Da...

INTRODUCTION Erectile dysfunction (ED) and the lower urinary tract symptoms caused by benign prostatic hyperplasia (LUTS/BPH) are highly prevalent among aging men. More data are needed from studies evaluating the impact of LUTS/BPH on ED. This study aimed to assess ED in patients with LUTS/BPH independent of comorbidities. MATERIAL AND METHODS During 2007 and 2008, we examined 10,932 patients...

AIM Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) is a hepatic secretory protein which promotes the degradation of low-density lipoprotein receptors leading to reduced hepatic uptake of plasma cholesterol. Non-synonymous single-nucleotide polymorphisms in its gene have been linked to hypo- or hyper- cholesterolemia, depending on whether they decrease or increase PCSK9 activity, respecti...

BACKGROUND Acne inversa (AI; also designated as Hidradenitis suppurativa) is a common chronic inflammatory skin disease, localized in the axillary, inguinal and perianal skin areas that causes painful, fistulating sinuses with malodorous purulence and scars. Several chronic inflammatory diseases are associated with the metabolic syndrome and its consequences including arteriosclerosis, coronary...