Pharmaceutical compounds represent a rapidly emerging class of environmental contaminants. Such compounds were recently classified by the U.S. Geological Survey, including several antibiotics. An LC-MS/MS screening method for the top five antibiotics in drinking water was developed and validated using a Shimadzu LC-MS-IT-TOF. The separation was performed using a Waters Acquity UPLC BEH C18 colu...

N-Nitrosodimethylamine (NDMA) is formed during chlorination of water containing the herbicide diuron (N'-(3,4-dichlorophenyl)-N,N-dimethylurea) but formation is greatly enhanced in the presence of ammonia (chloramination). Groundwater impacted by agricultural runoff may contain diuron and relatively high total nitrogen concentrations; this study examines the impact of the nitrogen form (ammoniu...

Swimming is generally considered to be a healthy leisure activity for both the young and old. Swimming is even often advised as the most appropriate sport for asthmatic children [1–3], mainly (but probably not solely) on the grounds that inhaling moist air is less conducive to triggering exercise-induced asthma [4]. However, for obvious reasons of microbiological safety, the water of public and...

Two methods were utilized to demonstrate the peroxidation of chloride ion to a free species (HOCl or Cl2) by myeloperoxidase. The peroxidase caused the volatilization of radioactivity from soultions containing hydrogen peroxide and [36Cl]NaCl, and catalyzed the formation of HOCl when solutions contianing these components were passed through a Millipore filter to which the peroxidase was adsorbe...

Cereal Chem. 87(5):409–414 Three factors (extent of chlorination, milling extraction rate, and particle-size reduction) in cake-baking functionality of Croplan 594W flour were explored using a Rapid Visco-Analyser (RVA) and time-lapse photography. The extent of chlorination and milling extraction rate showed dramatic effects, but postmilling to reduce flour particle size was a less significant ...

Copper-catalyzed ortho-benzoxylation of 2-arylpyridine sp(2) C-H bonds with acyl chloride is described. Notably, switching the base from t-BuOK to Li(2)CO(3) causes chlorination of the C-H bond to take place.