Abstract A new chitosan derivative bearing a thiadiazole compound was developed, and its antifungal larvicidal activities were investigated. The (coded here as PTDz-Cs) synthesized by the reaction between carboxylic of moiety chitosan. Fourier transform infrared spectroscopy (FT-IR), nuclear magnetic resonance ( 1 H/ 13 C-NMR), gas chromatography–mass spectrometry (GC–MS), elemental analysis, X...

Chitosan and its derivatives such as low molecular weight chitosans (LMWCs) have been reported to exert many biological activities, such as antioxidant and antitumor effects. However, complex and molecular weight dependent effects of chitosan remain controversial and the mechanisms that mediate these complex effects are still poorly defined. This study was carried out to investigate the immunos...

Polyelectrolyte multilayer microcapsules are made by layer-by-layer (LbL) assembly of oppositely charged polyelectrolytes onto sacrificial colloidal particles, followed by core removal. In this paper, we prepared contact killing polyelectrolyte microcapsules based solely on polysaccharides. To this end, water-soluble quaternized chitosan (QCHI) with varying degree of substitution (DS) and hyalu...

Chitin and chitosan oligosaccharides (COS) have been traditionally obtained by chemical digestion with strong acids. In light of the difficulties associated with these traditional production processes, environmentally compatible and reproducible production alternatives are desirable. Unlike chemical digestion, biodegradation of chitin and chitosan by enzymes or microorganisms does not require t...

Chitosans and pectins are natural polysaccharides which show great potential in drug delivery systems. Chitosans are a family of strongly polycationic derivatives of poly-N-acetyl-D-glucosamine. This positive charge is very important in chitosan drug delivery systems as it plays a very important role in mucoadhesion (adhesion to the mucosal surface). Other chitosan based drug delivery systems i...