Brief summary: This prospective cohort study leveraged data from the International Childhood Cardiovascular Cohorts (i3C) Consortium, including 42 324 participants at baseline and followed-up over a mean of 35 years, in order to investigate associations between cardiovascular risk factors (CVRF, body-mass index, systolic blood pressure, total cholesterol levels, triglycerides, smoking) childhoo...

Psoriasis and vitiligo are very common skin disorders that may have a profound impact upon the affected individuals; the etiology of both diseases includes genetic factors and triggers, which could be endogenous or exogenous. Two groups of children population consisting of 153 patients suffering from skin disorder (65 with vitiligo and 88 with psoriasis) have been examined at the Department of ...

Development of CKD may be programmed prenatally. We sought to determine the association of childhood CKD with prenatal risk factors, including birth weight, maternal diabetes mellitus (DM), and maternal overweight/obesity. We conducted a population-based, case-control study with 1994 patients with childhood CKD (<21 years of age at diagnosis) and 20,032 controls in Washington state. We linked m...

The challenges facing childhood immunization coverage, coupled with the dramatic resurgence of preventable diseases suggest that current strategies to ensure positive result in national immunization programmes in Nigeria needs to be examined. Immunization is one of the most cost-effective public health interventions to date, saving millions of lives and protecting countless children from illnes...

OBJECTIVE There is relatively little research on the childhood antecedent predictors of early-onset alcohol use. This study examined an array of psychosocial variables assessed at age 10 and reflecting Problem Behavior Theory as potential antecedent risk factors for the initiation of alcohol use at age 14 or younger. METHOD A sample of 452 children (238 girls) ages 8 or 10 and their families ...

Pedestrian injuries remain a significant public health problem for children.' In 1992 in the United States, more than 600 children younger than 16 years of age died2 and an estimated 31 000 were non-fatally injured3 from pedestrian injuries. In that country, pedestrian injuries account for 6 30o of childhood fatalities from all causes between 1-14 years, and 9-30o of deaths from all causes in c...

Childhood overweight and obesity have reached epidemic proportions, with nearly one of every three children in the USA being affected. That factors in the built environment are closely correlated to childhood obesity has become increasingly evident. Negative built environment factors disproportionately affect poor and minority children. This paper examines the current research on the state of c...

The National Institute of Neurological Disorders and Stroke and the Office of Rare Disorders sponsored a workshop on perinatal and childhood stroke in Bethesda, Maryland, on September 18 and 19, 2000. This was an international workshop to bring together experts in the field of perinatal and childhood stroke. Topics covered included epidemiology, animal models, risk factors, outcome and prognosi...