E. A. Weinstein, L. Liu, A. A. Ordonez, H. Wang, J. M. Hooker, P. J. Tonge, and S. K. Jain Center for Infection and Inflammation Imaging, Center for Tuberculosis Research, Department of Medicine, and Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA; Institute for Chemical Biology & Drug Discovery, Department of Chemistry, Stony Brook University, St...

Paeonia Radix is one of the most commonly used herbal drug in traditional Chinese medicine1 and folkloric medicine of different countries since ancient times2. A number of chemical and pharmacological studies have been conducted on the roots of Paeonia species. Monoterpen glycosides are the active constituents, among them; paeoniflorin is the main compound in genus Paeonia3. In traditional medi...

The concept of hormesis, or low-dose U-shaped responses, is now well established in toxicology and pharmacology but requires development in medicine and therapeutics. In doing so, care must be taken to not confuse metaphorical and chemical uses of the term hormesis. Low dose, continuous adaptive responses are fundamentally different than conventional pharmacology, and they may improve the scien...

A. Verónica Araya1, Teresa Massardo2, Jenny Fiedler3, Luis Risco4, Juan C. Quintana5 and Claudio Liberman1 1Endocrinology Section, Clinical Hospital of the University of Chile 2Nuclear Medicine Section, Clinical Hospital of the University of Chile 3Faculty of Chemical and Pharmaceutical Sciences, University of Chile 4Psychiatric Clinic of the Clinical Hospital of the University of Chile 5Depart...

nanobiotechnology appears to be an emerging science which leads to new developments in the field of medicine. importance of the magnetic nanomaterials in biomedical science cannot be overlooked. the most commonly used chemical methods to synthesize drugable magnetic nanobeads are co-precipitation, thermal decomposition and microemulsion. however monodispersion, selection of an appropriate coati...

Thomas L. Pallone,1 Malcolm R. Turner,2 Aurélie Edwards,3 and Rex L. Jamison4 1Division of Nephrology, University of Maryland School of Medicine, Baltimore, Maryland 21201; 2Department of Human Anatomy and Cell Biology, University of Liverpool, Liverpool L69 3GE, United Kingdom; 3Department of Chemical and Biological Engineering, Tufts University, Medford, Massachusetts 02155; and 4Division of ...

1 Section of Neonatology, Department of Pediatrics, Baylor College of Medicine, One Baylor Plaza, BCM 320, Houston, TX 77030, USA 2School of Biomedical, Biomolecular and Chemical Sciences (M310), The University of Western Australia, 35 Stirling Highway, Crawley, WA 6009, Australia 3Department of Pediatrics, Showa University of Medicine, Tokyo 142-8555, Japan 4Centre for Olfaction and Taste Scie...

Department of Toxicology, University of Cagliari, Italy, Department of Pediatrics and Clinical Medicine Section of Neonatal Intensive Care Unit, University of Cagliari, Italy, Department of Neurological Sciences, University of Cagliari, Italy, Department of Chemical Sciences, University of Cagliari, Italy, Pediatric Division, Pescia Hospital, Italy, Department of Biological Sciences, University...

1Laboratory for Drug Design and Synthesis, Centre for Chemical and Pharmaceutical Sciences, Central University of Punjab, Bathinda Punjab 151001, India 2Hematology-Oncology, Perelman School of Medicine, University of Pennsylvania, 720 BRB-II/III, 421 Curie Boulevard Philadelphia, PA 19104-6160, USA 3The Novo Nordisk Foundation Centre for Basic Metabolic Research, Section of Metabolic Genetics, ...

From the Department of Internal Medicine I, Div. of Hematology/Hemostasis (SE, VS, AW, PAK), the Ludwig-Boltzmann Institute for Thrombosis Research (SE, PAK), and the Department of Internal Medicine II, Div. of Angiology (EM), all University of Vienna, Vienna; the Wilhelminenspital, Department of Dermatology (CB), Vienna; the Hanuschkrankenhaus, Department of Angiology (MH), Vienna; the Institu...