ied this possibility by performing the enzymatic assay on controls containing increasing concentrations of ACET in the presence of different therapeutic concentrations of NAC (Fig. 1A). Evidently, NAC concentrations $100 mg/L cause a marked negative bias, reaching total suppression of the reaction in the presence of 10 g/L NAC. In contrast, similar concentrations of NAC have no effect on the AC...

Continuous glucose monitoring systems (CGMS) are becoming increasingly popular in diabetes management and helps understanding physiological responses towards nutrition intake of individual. Dietary plan insulin based on CGMS data to control prevent hyper/hypo glycemic risks. Commercial the market is useful for few days months. However, electromagnetic sensor can significantly extend life CGMS. ...

RESUMO Pacientes oncológicos desenvolvem problemas cardíacos frequentes devido à toxidade dos quimioterápicos, com consequente impacto na capacidade funcional (CF) e qualidade de vida (QV). O treinamento muscular inspiratório (TMI) pode ser um recurso terapêutico viável, já que estudos causa-efeito demonstraram melhora da CF QV em outras populações. Contudo, seu efeito ainda não foi avaliado pa...

BACKGROUND We performed a blood glucose meter hematocrit (HCT) interference test with lower sample manipulation requirements by using blood samples from patients with different blood glucose (BG) levels. METHODS Blood from five patients with different BG levels (2.8, 5.6, 8.3, 13.9, 19.4 mmol/liter) was manipulated to contain five different HCT concentrations (35/40/45/50/55%). Each sample w...

The CHEK2 gene encodes the CHK2 protein, which is kinase involved in DNA repair processes. By activating a lot of cell substrates, it can regulate the cell cycle, demonstrates suppressive effects, and participates in the senescence and apoptosis processes. Mutations in the CHEK2 gene are associated with increased risk of numerous cancers. The case described herein is that of a woman with a miss...

A commercially available agar-slide blood culture bottle (Septi-Chek; Roche Diagnostics, Div. Hoffman-La Roche, Inc., Nutley, N.J.) was compared with the radiometric blood culture system (BACTEC; Johnston Laboratories, Inc., Towson, Md.) in 8,544 paired blood cultures from adult patients. The systems were inoculated with equal volumes (10 ml) of blood. Overall, there was no statistically signif...

INTRODUCTION Localized involutional lipoatrophy of subcutaneous adipose tissue may develop due to subcutaneous injection of pharmaceutical preparations. The pathogenesis of this adverse drug reaction is unknown. The progression of localized involutional lipoatrophy ceases and occasionally it resolves after withdrawing the inducing agent. In case of localized involutional lipoatrophy due to subc...