cmt disease is the most common inherited neuromuscular disorder, with its estimated prevalence being 17–40:100,000. although it is genetically a highly heterogeneous disorder, the clinical phenotype is relatively homogeneous. this is characterized by wasting and weakness of distal limb muscles, involving especially the peroneal compartment (hence the old term of peroneal muscular atrophy), usua...

according to the well-known classification of dyck, inherited peripheral neuropathies can be categorized as hereditary motor and sensory neuropathies (hmsn) or charcot – marie – tooth (cmt) disease, hereditary motor neuropathies (hmn), and hereditary sensory neuropathies (hsn). cmt is a clinically and genetically heterogeneous group of motor and sensory neuropathies, and is the most common inhe...

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