Aptamers are nucleic acids that can bind to various molecules. Because they have some features that are lacking in antibodies, aptamers could serve as alternatives to antibodies. For the purpose of biosensing, we focused on aptamers that undergo structural changes on binding to their target molecules. We constructed an aptamer-based bound/free (B/F) separation system that uses a designed aptame...

background: the occurrence and the mortality related to breast cancer (bc) in iranian female population has increased over time. although there are many studies on bc and related risk factors, however, the epidemiological aspects of this melanoma in iranian females are uncertain. therefore, the aim of this study was to determine the relationship between demographical and clinical factors on the...

the aim of this study was to evaluate the variability of tavanmand engineering firm, due to instrumental changing in the way of control equipment from manually install to technical.  in this way, the theoretical literature review explores change management and resistance to change and methodology is based on quantitative data collection and analysis. the results of data analysis indicate that t...

Invasive prenatal diagnosis techniques include chorionic villus sampling (CVS), amniocentesis, cordocentesis or percutaneous umbilical blood sampling (PUBS), fetal tissue sampling, as well as embryoscopy and fetoscopy (Table 2). Some diagnostic results may be obtained by more than one technique: for example, fetal karyotype can be obtained from cells from amniocentesis, chorionic villus samplin...

a 22-year-old female patient presented to the emergency department of a tertiary care hospital with symptoms of headache and nausea. she has been on a regular follow-up for the preceding three and a half years after being diagnosed as systemic lupus erythematosus (sle). she had been treated earlier for sle nephritis in the same institution, and had two relapses of nephrotic syndrome in the last...