the most modern techniques in biotechnology owe their existence to the discovery of dna cloning and the genetic manipulation of organisms. however biotechnology is not new science in fact, many applications represent old practices with new methodologies. human have been used organisms for their benefit in many processes for several thousand years. therefore, one way of thinking about biotechnol...

The Cayley graphs Gm(G)=Cay(Gm,S) of Cartesian powers the finite group G with respect to canonical symmetric subsets S=S(m)⊂Gm are investigated. It is proved that for each m>1 graph Gm(G) determines up isomorphism. groups automorphisms Aut(Gm(G)) determined. shown if a non-abelian group, then Aut(Gm(G))≃(Gm⋊Aut(G))⋊Dm+1, where Dm+1 dihedral order 2m+2. If an abelian (with some exceptions m=3), ...

We have previously developed a genetically-engineered GFP-expressing telomerase-dependent adenovirus, OBP-401, which can selectively illuminate cancer cells. In the present report, we demonstrate that targeting a triple-negative high-invasive human breast cancer, orthotopically-growing in nude mice, with OBP-401 enables curative fluorescence-guided surgery (FGS). OBP-401 enabled complete resect...

Two issues may have a tremendous impact on the adequacy of retirement income for American workers. The first is the growth of 401(k) pension plans, which allow participants to contribute, before taxes, a portion of their salary to a qualified retirement account.1 By 1998, the most recent year that published information is available, 401(k) plans accounted for about 41 percent of all pension pla...

This is especially true in smaller companies and those of fairly recent vintage because 401(k)s are likely to be the only retirement program offered in these organizations. But, even in large and old-line businesses in which traditional defined benefit (DB) pension plans remain common, it’s important for employees to take responsibility for their retirement planning and save for retirement in o...

A sensitive and selective method was developed for the separation and characterization of related substances (RSs) in EVT-401 by hyphenated LC-MS techniques. Complete separation of the RSs was achieved with an Inertsil ODS-SP column (250 mm×4.6 mm, 5 µm) by linear gradient elution using a mobile phase consisting of 0.2% formic acid solution, methanol and acetonitrile. EVT-401 was found to be su...

in recent decades, biotechnologists have striven to improve the quantity and quality of food supply. producing genetically modified (gm) foods is one of the main goals and many countries all over the world have approved the distribution and consumption of the labeled gm foods in their own regions. however, there are still few groups having concerns about allergenicity of gm foods. this review h...