We describe a general construction of geometric U-folds compatible with the global formulation of four-dimensional extended supergravity on a differentiable spin manifold. The topology of geometric U-folds depends on certain fiber bundles which encode how supergravity fields are globally glued together. Smooth non-trivial U-folds of this type can exist only in theories where both the scalar and...

Within the ever-expanding repertoire of known protein sequences and structures, many examples of evolving threedimensional structures are emerging that illustrate the plasticity and robustness of protein folds. The mechanisms by which protein folds change often include the fusion of duplicated domains, followed by divergence through mutation. Such changes reflect both the stability of protein f...

MOTIVATION Identification and characterization of protein structure regularities can reveal the mechanisms governing protein structure, function and evolution. Here we focus on an intermediate level of regularity. We have developed automated methods to systematically construct a dictionary of supersecondary structures that can be used as 'protein parts' to describe fold-sized structures. RESU...

PURPOSE To review the occurrence of macular retinal folds following retinal detachment surgery. METHOD Review of the literature. RESULTS Macular folds have been reported in up to 3% of cases postoperatively. Risk factors are tamponading gas bubble, large exoplants, detachments with bullous configuration or running through the fovea, and incomplete drainage of subretinal fluid. Preventive me...

background with the advent of hystroscopic surgery, abnormalities confined to the uterine cavity such as endometrial polyps, submucous myomas, uterine septae and synechia , were supposed to be treated effectively. diagnostic hysteroscopy is the gold standard for investigating the intrauterine diseases as it allows for biopsy and removal of lesions. objectives forty premenopausal women without t...

our case was a 48-year-old man with cervical pain radiatingto the upper limbs. imaging showed an intradural tumor with extradural component encasing the vertebral artery.thetumor diagnosed asa neurinomaand had been removed surgically.the post operationmagnetic resonance imagingshowed that the tumor was completely removed andthe vertebral arterywas intact at theentire length.the goal of surgery ...

abstract our patient was a 43-year-old woman with a suboccipital headache and pain in the upper cervical region from 3 years ago with a progressive generalized weakness in the last 3 months. neuroimaging study showed a dumbell shaped lesion with compression of the spinal cord in the cervical region that was identified as a neurinoma. the tumor had been completely removed by surgery but after th...

Employing the method applied to M5-branes recently by Bah, Bonetti, Minasian and Nardoni, we study M2-branes on a disk with non-trivial holonomies at boundary. In four-dimensional $U(1)^4$-gauged $\mathcal{N}=2$ supergravity, find supersymmetric $AdS_2$ solutions from wrapped topological in Calabi-Yau two-, three- four-folds. We uplift eleven-dimensional supergravity. For four-folds, Bekenstein...