نتایج جستجو برای: cell survival fraction

تعداد نتایج: 2016629  

2001
Marc P. Pelletier Michael D. deB. Edwardes René P. Michel Fawaz Halwani Jean E. Morin

in resectable non-small cell lung cancer (NSCLC). Design: A cohort of patients with resectable NSCLC was prospectively followed up for 8 years (100% follow-up). Setting: A university hospital in a large Canadian city. Patients: One hundred and thirteen consecutive patients who underwent surgical resection of primary NSCLC. Main outcome measures: Presence of peritumoral B lymphocytes (identified...

Intracellular reactive oxygen species (ROS) play an important role in cancer stem cell (CSC) function. Hesperetin (Hst) is a flavonoid that has been shown to affect cellular ROS level. The goal of this study was to investigate the effect of Hst on the level of ROS in gastric CSCs (GCSCs). MTT assay was used to evaluate cell survival. Cellular ROS level was measured using 2′,7′-dichlorofluoresci...

Journal: :Cancer research 1984
Y Sano T Hoshino M Barker D F Deen

This study was designed to examine the relative effect of each of four fractions of 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) against 9L rat brain tumor multicellular spheroids and to compare the results of the cell survival and growth delay assays. Similar levels of cell kill resulted when BCNU was administered either as single fractions of 1.5, 3.0, 4.5, or 6.0 micrograms/ml for 1 hr or as ...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه پیام نور - دانشگاه پیام نور استان تهران - دانشکده زیست شناسی 1388

126 abstract: in this research we studied the effects of cyclic hydration and dehydration of cysts of artemia urmiana and artemia parthenogenetica on the hatching percentage, survival and growth. the experiment was carried out in 3 treatments (1-3 hydration/dehydration cycles) with 3 replicates for each treatment. later effects of cold preservation at -20°c during three time periods were ...

Objective(s): In the current study antioxidant capacities of five different extracts of Artemisia ciniformis aerial parts were evaluated by cell-free methods. Then seven fractions of the potent extract were selected and their antioxidant capacity was assayed by cell free and cell based methods. Materials andMethods: Antioxidant ability was measured using the: 2, 2-diphenyl-1-picrylhydrazyl (DP...

Journal: :Methods in molecular medicine 2005
Anupama Munshi Marvette Hobbs Raymond E Meyn

The clonogenic cell survival assay determines the ability of a cell to proliferate indefinitely, thereby retaining its reproductive ability to form a large colony or a clone. This cell is then said to be clonogenic. A cell survival curve is therefore defined as a relationship between the dose of the agent used to produce an insult and the fraction of cells retaining their ability to reproduce. ...

Journal: :World Journal of Surgical Oncology 2009
Hang Joo Cho Sin Young Kim Kee Hwan Kim Won Kyung Kang Ji Il kim Seong Tack Oh Jeong Soo Kim Chang Hyeok An

BACKGROUND The overall level of chromatin compaction is an important mechanism of radiosensitivity, and modification of DNA methylation and histone deacetylation may increase radiosensitivity by altering chromatin compaction. In this study, we investigated the effect of a demethylating agent, a histone deacetylase(HDAC) inhibitor, and the two agents combined on radiosensitivity in human colon a...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2008
Julien Fitamant Céline Guenebeaud Marie-May Coissieux Catherine Guix Isabelle Treilleux Jean-Yves Scoazec Thomas Bachelot Agnès Bernet Patrick Mehlen

Netrin-1, an axon navigation cue was proposed to play a crucial role during colorectal tumorigenesis by regulating apoptosis. The netrin-1 receptors DCC and UNC5H were shown to belong to the family of dependence receptors that share the ability to induce apoptosis in the absence of their ligands. Such a trait confers on these receptors a tumor suppressor activity. Expression of one of these dep...

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