Background: HLA-G is a nonclassical HLA class I molecule which, when elevated in tumor cells, is one of the main factors involved in tumor evasion of immune responses including NK and T cells. Objective: To evaluate the effect of HLA-G downregulation on NK cell cytotoxicity in tumor cell lines. Methods: The expression level of HLA-G was measured by real-time PCR and flowcytometry after transfec...

The present study focuses on the receptor driven endocytosis typical of viral entry into a cell. A locally increased density receptors at time contact between cell and virus is necessary in this case. considered as substrate with fixed its surface, whereas host are free to move over membrane, allowing local change their concentration. In zone membrane inflects forms an envelope around virus. cr...

Physical models can help us to infer, from the shape of outer membrane, which biological processes happen inside living cell.

this is a comprehensive review of the recent progresses made in the field of zeolite membranes. it describes zeolitic materials and methods of membrane fabrication, followed by a summary of applications for gas separation, pervaporation and separation of liquid mixtures. special attention is called to polymer mixed matrix membranes (mmms) and membranes based on metal organic frame works (mofs)....

Numerical modeling has been a vital tool in proton-exchange-membrane fuel-cell (PEMFC) analysis; however, the predictive capabilities of these models depend on input physical parameters, several which are either not experimentally measured or have large scatter values. This article presents an uncertainty propagation-based sensitivity analysis to identify model parameters that impact prediction...

objective: today, esophageal cancer (ec) has become one of the most common cancer types in china. therefore, new drug and therapeutic strategies are urgently needed to improve postoperative survival rate of patients with ec. as a food additive, several lines of evidence have shown that citric acid can be served as glycolysis suppressor to inhibit growth of some tumor cells. however, little is k...