Chagas disease, caused by the protozoan Trypanosoma cruzi, is endemic in Latin America and affects ca. 10 million people worldwide. About 30% of Chagas disease patients develop chronic Chagas disease cardiomyopathy (CCC), a particularly lethal inflammatory cardiomyopathy that occurs decades after the initial infection, while most patients remain asymptomatic. Mortality rate is higher than that ...

Compound Chuanxiong Capsule (CCC), a Chinese herbal compound, can exhibit antiatherosclerotic effect; however, its mechanism is still unclear. This study is designed to study the mechanism of CCC on atherosclerosis in the ApoE-knockout (ApoE(-/-)) mice fed with a high-fat diet. After 6 weeks of high-fat feeding, 40 ApoE(-/-) mice were randomized (n = 10) and treated with lipitor, high-dose or l...

HOXD10, a key regulator of cell-differentiated phenotype maintainence, has been demonstrated to be involved in the tumorigenesis of many human malignacies. However, the status of HOXD10 expression and its biological function in cholangiocellular carcinoma (CCC) remain to be clarified. In the present study, we investigated the clinical significance and biological functions of HOXD10 in CCC and f...

Decision procedures for monitoring industrial processes can be based on application of control charts. The commonly used p-chart and np-chart are unsatisfactory for monitoring high-quality processes with a low fraction nonconforming. To overcome this difficulty, one may develop models based on the number of items inspected until r (P 1) nonconforming items are observed. The cumulative count con...

BACKGROUND Within the field of oncology, increasing access to high quality care has been identified as a priority to reduce cancer disparities. Previous research reveals that the facilities where patients receive their cancer care have implications for cancer outcomes. However, there is little understanding of how patients decide where to seek cancer care. This study examined the factors that s...

The present study was carried out to evaluate the effect of abscisic acid (ABA) and chlorocholine chloride (CCC) on growth, nodulation and changes in endogenous level of plant hormones indole acetic acid (IAA) and Gibberellic acid (GA) of mung bean grown under normal or water stress conditions. Two varieties (cv.NM 98 and cv.HCM 209) of mung bean were soaked in 10 M ABA or in chlorocholine chlo...