The current drugs against sleeping sickness are derived from cancer chemotherapeutic approaches. Herein, we aimed at evaluating the in vitro effect of alcoholic extracts of Artemisia annua (AMR), Rumex abyssinicus (RMA), and Catha edulis Forsk (CEF) on proliferation/viability of 1321N1 astrocytoma, MCF-7 breast cancer, THP-1 leukemia, and LNCaP, Du-145, and PC-3 prostate cancer cells and on Try...

Globally, road crashes are the ninth single biggest cause of death, killing 1.2 million people annually. The World Health Organization estimates that this could rise to 2.4 million by 2020, with 85% of this increase being in lowand middle-income countries. Road traffic crashes cost developing countries a staggering 1–2% of their gross domestic product.1 However, relative to the burden of diseas...

INTRODUCTION Khat (Catha edulis) is widely used in East Africa and the Middle East, often in combination with tobacco smoking. Sleep disturbance has been linked with habitual khat use; however, no systematic attempt has been made to test the hypothesis that use of khat and khat and tobacco in combination are related to sleep disturbance. Sleep disturbances are associated with dysregulations in ...

OBJECTIVE Chewing fresh leaves of the Khat plant (Catha edulis), represents a widespread habit with a deep-rooted sociocultural tradition in Yemen. Khat is chewed for its central stimulant properties and to dispel feeling of fatigue and its use is believed to be associated with disturbance of mood. We studied the effect of chewing Khat leaves on human mood by using a standard questionnaire meth...