PURPOSE OF THE REVIEW Time-resolved 3D velocity-encoded MR imaging with velocity encoding in three directions (4D Flow) has emerged as a novel MR acquisition technique providing detailed information on flow in the cardiovascular system. In contrast to other clinically available imaging techniques such as echo-Doppler, 4D Flow MRI provides the 3D Flow velocity field within a volumetric region of...

Accurate assessment of left ventricular function in rodent models is essential for the evaluation of new therapeutic approaches for cardiac diseases. In our study, we provide new insights regarding the role of a 1.5 Tesla (T) magnetic resonance imaging (MRI) device and different anesthetic regimens on data validity. As dedicated small animal MRI and echocardiographic devices are not broadly ava...

Background Cardiac stress MRI has grown to a well established method to detect hypokinesia or perfusion deficits due to ischemia. Commonly, myocardial load is generated by the administration of adenosine or dobutamine, which is associated by a higher complication rate compared to exercise stress testing. Our purpose was to evaluate the use of an MR conditional pedal ergometer for cardiac stress...

Background Clinical and experimental observations of preand afterload independent indices of impaired cardiac contractile performance and hemodynamic dysfunction are limited by the poor true temporal resolution of cine MRI. We aimed to develop and optimize for the first time an imaging and reconstruction protocol for MRI real time measurement of cardiac pressure-volume relations and to compare ...

Background MRI has generally been contraindicated in patients (pts) with pacemakers (PM) or defibrillators (ICD) due to concern of a variety of potential complications. Several recent series have suggested potential safety of MRI in pts with cardiac devices, but most excluded cardiac or thoracic imaging. Additionally there is very limited data on safety of CMR in pts with devices, especially in...

Introduction: Along with the increased use of cardiac imaging at clinics there is increased attention to the potential risks related to the methods used like magnetic resonance (MR) and it cannot be ruled out that MR can alter DNA structure. The aim of this review is to assess the impact of routine cardiac magnetic resonance (CMR) scanning on DNA damages in human T lymphocytes....

Delayed enhancement magnetic resonance imaging (DE-MRI) has excellent spatial resolution and compared with other cardiac imaging techniques it can detect a small myocardial infarction (MI) or a subendocardial infarction. A 76-year-old man was admitted for loss of consciousness because of cardiac tamponade. The cause of tamponade was unknown, but electrocardiography and blood test suggested a re...

Background and purpose In patients with systemic sclerosis (SSc) and rheumatoid arthritis (RA), cardiac involvements are common, may have serious consequences. Sensitive diagnostic techniques in cardiac MRI can identify subclinical myocardial abnormalities. The purpose of this study is to assess regional dysfunction of left ventricule in asymptomatic patients with SSc, compared to RA, by using ...

Primary cardiac neoplisms are uncommon, with a reported prevalence of 0.0017-0.28% of autopsies (1). Approximately 15% of these are benign tumors, of which the most common is myxoma. Cardiac fibroma is a rare benign tumor that primarily occurs in infants and children. Imaging modalities used for diagnosis of cardiac masses include echocardiography, computed tomography, and magnetic resonance im...

Background—Transgenic mice expressing tumor necrosis factor-a (TNF-a) in cardiac myocytes develop dilated cardiomyopathy, but the temporal progression to cardiac dysfunction is not well characterized. We asked (1) Does magnetic resonance imaging (MRI) provide a reproducible assessment of cardiac output in mice that correlates with invasive measurements obtained with thermodilution? (2) What is ...