Highlight Research Brown seaweed heavy metals content varies between species Risk assessment showed low health risk for metal from intake of the three brown The types did not show carcinogenic properties to Arsenic (As) Abstract Marine are known as one potential biological agents be developed functional food and medicinal sectors. This study aims examine concentration (Pb, Cd, Hg, As) in algae ...

It is generally accepted that cancer incidences in various organs show strong geographical variations. Studies on immigrants show that different cancer incidences in various global regions are heavily dependent on the life-style and that the human diet is considered to be an important cause of human cancer (Wynder & Gori, 1977: Doll & Peto, 1981). According to our opinion, there are four major ...

Information on the causes of cancer at specific sites is important to cancer control planners, cancer researchers, cancer patients, and the general public. The International Agency for Research on Cancer (IARC) Monograph series, which has classified human carcinogens for more than 40 years, recently completed a review to provide up-to-date information on the cancer sites associated with more th...

BACKGROUND A recent attempt to estimate the false-positive rate for cancer epidemiology studies is based on agents in International Agency for Research on Cancer (IARC) category 3 (agent not classifiable as to its carcinogenicity to humans) in the IARC Monographs Program. METHODS The estimation method is critiqued regarding biases caused by its reliance on the IARC classification criteria for...

The group of pattern recognition receptors includes families of Toll-like receptors, NOD-like receptors, C-type lectin receptors, and RIG-I-like receptors. They are key sensors for a number of infectious agents, some of which are carcinogenic, and they launch an immune response against them. Inherited structural variation in genes encoding these receptors and proteins of their signaling pathway...

The knowledge on the etiology of breast cancer has advanced substantially in recent years, and several etiological factors are now firmly established. However, very few new discoveries have been made in relation to occupational risk factors. The International Agency for Research on Cancer has evaluated over 900 different exposures or agents to-date to determine whether they are carcinogenic to ...

3,2'-Dimethyl-4-aminobiphenyl (DMAB) is a potent carcinogenic aromatic amine which demonstrates multiorgan tropism in rats. Using polyclonal antibodies against DMAB-DNA adducts, an immunohistochemical procedure as well as an ELISA were applied to investigate the relationship between DMAB-DNA adduct formation and tumorigenicity. Dose-related nuclear staining was observed 24 hr after application ...

It is generally accepted that cancer incidences in various organs show strong geographical variations. Studies on immigrants show that different cancer incidences in various global regions are heavily dependent on the life-style and that the human diet is considered to be an important cause of human cancer (Wynder & Gori, 1977: Doll & Peto, 1981). According to our opinion, there are four major ...

Risk assessment models strive to predict risks to humans from toxic agents. Safety factors and assumptions are incorporated into these models to allow a margin of error. In the case of cancer, substantial evidence shows that the carcinogenic process is a multistage process driven by the interaction of exogenous carcinogenic exposures, genetic traits, and other endogenous factors. Current risk a...