The two unique Ni(II) atoms of the title complex, [MnNi(2)(C(11)H(8)N(3)O(6))(2)(H(2)O)(4)]·4H(2)O, have a slightly distorted square-planar coordination environment with a tetra-dentate N-(5-nitro-2-oxidobenzyl-idene)glycylglycinate Schiff base trianion. The Ni(II) atoms are coordinated by one phenolate O atom, one imine N atom, one amido N atom and one carboxyl-ate O atom. The Mn(II )atom is c...

In the title compound, {[NiTb2(C14H8N2O5)4(H2O)4]·4H2O} n , the Tb(III) ion is coordinated by one water mol-ecule and seven O atoms from four 5-(pyridine-4-carboxamido)-isophthalate (L) ligands in a distorted square-anti-prismatic arrangement, while the Ni(II) ion, lying on an inversion center, is six-coordinated in an octa-hedral geometry by two pyridine N atoms, two carboxyl-ate O atoms and t...

In the crystal structure of the title compound, C(6)H(9)N(2) (+)·0.5C(4)H(2)O(4) (2-)·0.5C(4)H(6)O(4), the fumarate dianion and fumaric acid mol-ecule are located on inversion centres. The 2-amino-5-methyl-pyrimidinium cation inter-acts with the carboxyl-ate group of the fumarate anion through a pair of N-H⋯O hydrogen bonds, forming an R(2) (2)(8) ring motif. These motifs are centrosymmetricall...

The title compound, C(10)H(9)N(3)O(2), was synthesized from azido-benzene and ethyl acetyl-acetate. A pair of hydrogen bonds [2.617 (2) Å] inter-connects a pair of the carboxyl groups, forming an R(2) (2)(8) inversion dimer, a frequent motif in carboxylic acids. In the title structure, the bonding H atom in the aforementioned O-H⋯O hydrogen bond is significantly shifted towards the acceptor O a...

The dinuclear complex in the title compound, [Mn(2)(C(16)H(6)N(2)O(8))(H(2)O)(10)]·4H(2)O, lies on an inversion center. Two delocalized carboxyl-ate groups are each connected in a monodentate fashion to two similar penta-aqua-manganese units, whereas the other two localized carboxyl-ate groups are uncoordinated. The metal ion has octa-hedral coordination, with the O atom of a carboxyl-ate group...

In the title compound, {[Ag(C(6)H(4)NO(2))(C(6)H(12)N(4))(H(2)O)]·2H(2)O}(n), the Ag(I) atom shows a distorted triangular pyramidal geometry,, formed by two N atoms from two hexa-methyl-ene-tetra-amine (hmt) ligands and one N atom from a pyridine-4-carboxyl-ate (4-pdc) ligand and one water mol-ecule. The hmt ligands bridge the Ag atoms, forming a chain along [001]. The carboxyl-ate group of the...

In the title complex, [Ca(C(10)H(6)NO(2))(2)(H(2)O)(2)](n), the Ca(II) ion is eight-coordinated by six carboxyl-ate O atoms from four separate quinoline-3-carboxyl-ate ligands, two of which are bidentate chelate and two bridging, and two water mol-ecules in a distorted square-anti-prismatic geometry. The bridging groups form a polymeric chain substructure extending along the c axis, the chains ...

A number of carboxyl-substituted S-blocked glutathiones have been shown to be competitive inhibitors of yeast glyoxalase I at 25 degrees C, pH 6.6. Amidation of the glycyl carboxyl group of S-(p-bromobenzyl)glutathione has no appreciable effect on binding whilst methylation reduces binding by 8.9-fold, indicating a steric constraint and the possible presence of a hydrogen bond in this region of...

The crystal structure of recombinant rat prostatic acid phosphatase in complex with the inhibitor L(+)-tartrate was determined to 3-A resolution with protein crystallographic methods. The inhibitor binds at the carboxyl end of the parallel strands of the alpha/beta domain. One of the carboxyl groups of the tartrate molecule interacts with the conserved residues Arg-11, His-12, and Arg-15, which...

During the formation of the title salt, C(7)H(10)N(+)·C(3)H(3)O(4) (-), an H atom of a carboxyl group was transferred to the amino group. All non-H atoms of the cation are essentially coplanar [r.m.s. deviation = 0.007 (4) Å]. The mean planes of the carboxyl-ate and carboxyl groups of the anion form a dihedral of 69.67 (1)°. In the crystal, N-H⋯O and O-H⋯O hydrogen bonds connect the anions and ...