Purpose: To formulate topical gels containing various essential oils and evaluate their antibacterial activity against methicillin-resistant Staphylococcus Aureus (MRSA) skin infections. Methods: The four essential oils namely, lemon grass, rosemary, thyme and basil were steam-distilled and then evaluated for their antibacterial activity against MRSA. Lemon grass and thyme oils were chosen for ...

Naproxen sodium is a non steroidal antiinflammatory drug, used in the treatment of inflammatory and degenerative disorders of the musculoskeletal system. It is widely prescribed for the treatment of osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, gout, extra-articular disorders, bursitis, tendonitis, and non articular rheumatic condition. Naproxen sodium has some side effects when...

Conventional ophthalmic solutions often eliminate rapidly after administration and can’t provide and maintain an adequate concentration of drug in the precorneal area. This can be overcome by the use of in situ gel forming systems that are instilled as drops into the eye and undergo a sol-gel transition in the culde-sac. The present work describes the formulation and evaluation of an ophthalmic...

Acyclovir (ACV), a model drug for this study, is one of the most effective drugs against viruses of the herpes group. Absorption of orally administered ACV is variable and incomplete, with a bioavailability of ca. 15-30%. The drug is absorbed in the duodenum after oral administration and hence, preparation of a floating drug delivery system (FDDS) for ACV may increase oral absorption of the dru...

BACKGROUND Periodontitis is a disease of tooth supporting tissues, and Gram-negative Bacteria are the main cause of this. Propolis has antibacterial, anti-inflammatory, and antioxidant effects due to its high polyphenol and flavonoids content. The aim of this study is the formulation of a mucoadhesive gel containing concentrated extract of propolis for treatment of periodontitis. MATERIALS AN...

Mucoadhesive durg delivery systems are among novel drug delivery systems that due to their ability to adhere and remain on the mucosal surfaces and a show and sustained release of their drug contect have attracted special attention in recent years.the aim of this study was to evaluate the effect of four different important factors on the  mucoadhesive strength of a few  mucoadhesive polymers.am...