The extracellular calcium-sensing receptor (CaR; alternate gene names, CaR or Casr) is a membrane-spanning G protein-coupled receptor. CaR is highly expressed in the parathyroid gland, and is activated by extracellular calcium (Ca(2+)(o)). Mice homozygous for null mutations in the CaR gene (CaR(-/-)) die shortly after birth because of the effects of severe hyperparathyroidism and hypercalcemia....

The purpose of this paper is to examine the use of Light Detection And Ranging (LiDAR) in obstacle detection systems in autonomous vehicles (AVs). Particular attention will be given to methods being developed to detect nonmotorized bodies such as pedestrians and cyclists due to unique variables they present compared to other vehicles. Due to the increasing societal and professional relevance of...

The compatibility problems of the mini car in car-tocar frontal collision and car-pedestrian accident are discussed using accident data and computer simulations. In our analysis of the accident data in Japan, the number of fatalities was investigated using the vehicle masses and classes. It was found that the cars with identical mass are most compatible since the injuries per accident are minim...

Adenovirus is an important respiratory pathogen. Adenovirus fiber from most serotypes co-opts the Coxsackie-Adenovirus Receptor (CAR) to bind and enter cells. However, CAR is a cell adhesion molecule localized on the basolateral membrane of polarized epithelia. Separation from the lumen of the airways by tight junctions renders airway epithelia resistant to inhaled adenovirus infection. Althoug...

To broaden our repertoire of monoclonal antibodies against CAR (coxsackievirus and adenovirus receptor), we inoculated mice with an expression vector containing the cDNA encoding human CAR extracellular and transmembrane sequence, and boosted the response by inoculation with soluble human CAR protein produced in E. coli. Of the hybridomas obtained following this immunization protocol, one secre...

the synthetic seed technology is becoming popular due to its wide application in germplasm conservation and for exchanges between countries in the floriculture trade. in this study, this method was used to study the germination and conversion capabilities of orchid species dendrobium white fairy when stored at different storage times and with different storage containers. a high germination per...