BACKGROUND The purpose of this study was to assess the therapeutic efficacy of oral versus intravaginal voriconazole and compare it with fluconazole for the treatment of experimental vaginitis caused by a fluconazole-resistant Candida albicans isolate. METHODS Mice were treated with voriconazole at 5, 10 and 20 mg/kg once a day and 20 mg/kg twice a day or with fluconazole at 20 mg/kg once or ...

Vaginitis is the most prevalent disorder among the pregnant women. The objective of this study was to find out the prevalence of common types of vaginitis among the pregnant women visiting Paropakar Maternity and Women's Hospital in Kathmandu. Among 200 pregnant women included in the study, 78 (39.0%) had vaginitis. Of total 78 positive cases of vaginitis, 29.5% had candidiasis, 52.6% bacterial...

The vast majority of vaginal fungal infections are caused by Candida species. However, vaginitis cases caused by molds are extremely rare. Aspergillus protuberus is previously known as a member of Aspergillus section Versicolores which can cause opportunistic infections in immunocompromised patients, however it has recently been described as a seperate species. Although the members of Aspergill...

Ten instances of bronchopulmonary moniliasis due to C. albicans in neonatal infants, 1 to 11 days of age, are described. The incidence was 1.05% out of a total of 947 consecutive necropsies on neonates. Diagnosis was established by morphological identification of the fungi. Seven cases were associated with inflammatory exudation. In three cases inflammation was absent. Infection secondary to mo...

background and objectives: secreted aspartyl proteinase (sap) is one of the main virulence factors in the pathogenesis of candida. this enzyme is encoded by a family of at least ten genes. among these genes, the role of sap1-3 in mucosal infections is evident. this study aimed to investigate the expression of sap1-3 genes of candida albicans isolates after treatmentwith echinophora platyloba ex...

BACKGROUND & OBJECTIVES Women who do not seek treatment for recurrent vaginitis have risk to acquire other sexually transmitted infections. Besides proper antibiotic treatment, male condom acts as a barrier to various infections. Present study was done to assess type of vaginitis, its association with various contraceptive methods and need of male condom in prevention of recurrent vaginitis. ...

Desquamative inflammatory vaginitis is a poorly understood chronic vaginitis with an unknown etiology. Symptoms of desquamative inflammatory vaginitis include copious yellowish discharge, vulvovaginal discomfort, and dyspareunia. Cervical ectropion, the presence of glandular columnar cells on the ectocervix, has not been reported as a cause of desquamative inflammatory vaginitis. Although cervi...

Aerobic Vaginitis vaginitis is closely related to the imbalance of vaginal microenvironment. In article 2202432 by Tong-Yi Sun, Yuanyuan Gao, Li-Li Li, and co-workers, a dynamically responsive core–shell nanogel (CSNG) designed. CSNG can achieve controlled temporal release antimicrobial peptide prebiotic, which high selective sterilization pathogenic bacteria promote growth beneficial simultane...

Twelve slow-growing virus isolates propagated in tissue culture from cattle with epididymitis and vaginitis were identified as herpes viruses by virtue of their biological, physicochemical and morphological characteristics. None of the 12 virus strains proved to be serologically related to the infectious pustular vulvo-vaginitis-infectious bovine rhinotracheitis (IPV-IBR) virus, but a further 3...