breast cancer is characterized by a distinct metastatic pattern involving the regional lymph nodes, bone marrow, lung and liver. tumour cell migration and metastasis share many similarities with leukocyte trafficking, which is critically regulated by chemokines and their receptors. detection of breast cancer and its metastasis at the earliest stage is important for the management and prediction...

conclusions physicians should be aware of this rare site of metastasis. early diagnosis is of paramount importance in order to effectively prevent the significant morbidity this condition can cause if left untreated. introduction small cell carcinoma constitutes the most aggressive type of lung cancer, with the greatest propensity for early disseminated disease. although commonly neglected due ...

Abstract Metastasis is responsible for the majority of breast cancer–related deaths, however, mechanisms underlying metastasis in this disease remain largely elusive. Here we report that under hypoxic conditions, alternative splicing MBD2 suppressed, favoring production MBD2a, which facilitates cancer metastasis. Specifically, MBD2a promoted, whereas its lesser known short form MBD2c suppressed...

Journal of Cancer Metastasis and Treatment is an open access journal, focusing on basic clinical studies related to cancer cell, cell biology, oncology, radiation therapy radiology, obstetrics gynecology, pediatrics, surgery, hematology, neuro-oncology, etc.

Journal of Cancer Metastasis and Treatment is an open access journal, focusing on basic clinical studies related to cancer cell, cell biology, oncology, radiation therapy radiology, obstetrics gynecology, pediatrics, surgery, hematology, neuro-oncology, etc.

Background: Renal cancer is one of the most common malignant tumors urinary system, with distant metastasis occurring 30% patients. Therefore, early detection and monitoring tumor progression are great significance in diagnosis treatment renal cancer. However, current biomarkers used to diagnose, monitor recurrence assess prognosis still uncertain. Circulating cells (CTCs) detached from primary...

background: although the cox proportional hazard regression is the most popular model for analyzing the prognostic factors on survival of cancer patients, under certain circumstances, parametric models estimate the parameter more efficiently than the cox model.  the aim of this study was to compare the cox regression model  with parametric models in patients with gastric cancer who registered a...