The melanoma antigen gene (MAGE) A1-A6 RT-PCR system was developed for the detection of lung cancer cells in the sputum. However, we identified MAGE expression in some patients with non-malignant lung diseases. To understand these patterns of MAGE expression, we performed MAGE A3 methylation-specific PCR (MSP) and p16 MSP. We collected 24 biopsy s...

-Cancer is a class of diseases characterized by out-of-control cell growth. There are over 200 different types of cancer, and each is classified by the type of cell that is initially affected. This paper discusses the technical aspects of some of the ontology-based medical systems for cancer diseases. It alsoproposes an ontology based diagnostic methodology for cancer diseases. This methodology...

Summary The term Tc17 cells refers to interleukin 17 (IL-17)-producing CD8 + T cells. While IL-17 is an important mediator of mucosal defense, it also centrally involved in driving the inflammatory response immune-mediated diseases, such as psoriasis, multiple sclerosis, and bowel disease. In this review, we aim gather current knowledge on phenotypic transcriptional profile, vitro vivo generati...

BACKGROUND Many studies try to identify cancer diagnostic biomarkers by comparing peripheral whole blood (PWB) of cancer samples and healthy controls, explicitly or implicitly assuming that such biomarkers are potential candidate biomarkers for distinguishing cancer from nonmalignant inflammation-associated diseases. METHODS Multiple PWB gene expression profiles for lung cancer/inflammation-a...

The article presents up-to-date information on the structure of C-reactive protein, its functions and role in risk stratification cardiovascular diseases, cancer mental disorders.

The most essential need for Humans to survive on this evergreen Earth is Air, Water, Food and Shelter. In the above factors, food plays a core role in Human Health. habits which are followed nowadays give map reach diseases; due Modern foods include fast foods, preserved deep-fried packed snacks. Unhygienic cooking can also lead contamination of causes serious health issues all humans. This sho...

abstract breast cancer is a multifactorial disease. benign breast disease (bbd) is one of the most important risk factors for breast cancer. the etiology of bbd is unknown. it is divided into nonproliferative and proliferative diseases. the selection of studies will be based on titles, abstract screening, inclusion and exclusion criteria, and quality assessment. previous studies have shown that...

background: breast cancer is the most common cancer among women worldwide. because of unknown etiology of cancer there is no specific existing method to prevent this diseases. annual mammography is considered the most valuable tool for detecting breast cancer in the earliest possible stages. this study was conducted to determine the effects of an education program on promoting mammography behav...

background: ovarian cancer is a relatively common cancer among postmenopausal women. nowadays, there is controversy about immunotherapy of ovarian cancer patients with interleukins such as interferon to reach better out come in prognosis of patients under chemotherapy. ctla-4 is a gene, which has an important role in homeostasis and regulation of immune response. inhibitory nature of ctla-4 is ...