abstract background: children suffering from cancer frequently use complementary and alternative medicine (cam). most of people do not disclose using cam to their physicians as they fear to be blamed or prohibited using them. some of these products may interfere with the conventional remedies. the aim of this study was to investigate the frequency and characteristics of cam use in pediatric onc...

there are many techniques for reconstruction after total pharyngolaryngoesophagectomy. the use of a transposed stomach to restore gastrointestinal continuity, and this combined cervical and abdominal approach for pharyngolaryngoesophagectomy and gastric pull up has become one of the most popular. this retrospective study is a review of 50 consecutive iranian patients who underwent pharyngolaryn...

conclusions pet/ct can provide diagnosis and more accurate staging, location of tumor with its capability in providing the anatomical and physiological information synchronizes. therefore pet/ct plays an important role in oncology. objectives in this paper, we evaluate application of pet/ct for improve oncologic imaging. methods the papers were searched in pubmed and scopus databases with the r...

Benzene, Toluene, Ethyl Benzene and Xylene are volatile organic compounds (VOCs) with approximately similar physical and chemical characteristics. Benzene and Ethyl-benzene are known carcinogen as well as they affect the circulatory, nervous, and reproductive and respiratory systems. Toluene and Xylene also damage the nervous and reproductive systems. The main purpose of this study is to determ...

conclusions our results suggest that h. parva and h. oculata may be promising therapeutic candidates for the treatment of hcc, following further confirmatory in vivo experiments and clinical trials. results our results showed that h. parva methanolic extracts (250, 500, and 1000 µg/ml) and h. oculata methanolic extracts (200, 400, and 800 µg/ml) increased reactive oxygen species (ros) formation...

background: attempts for early detection of gastric cancer have recently focused on host's genetic susceptibility factors and gene-environment interactions. we have, herein, studied the association of mthfr c677t single nucleotide polymorphism (snp) and its interaction with helicobacter pylori infection, smoking, age and gender on the risk of gastric cancer among an iranian population. met...

aim :  to evaluate the association of dnmt1 and mgmt amino acid substitution polymorphisms and colorectal cancer in iranian population. background : the mgmt and dnmt1 are two important methyltransferase enzymes. amino acid substitution polymorphisms in mgmt and dnmt1 genes may be associated with the genetic susceptibility to sporadic colorectal cancer. patients and methods : we assessed eight ...

the mitochondrial dna (mtdna) mutations in mitochondrial coding and non coding regions seem to be important in carcinogenesis. the aim of this investigation was to evaluate coding region (mt-trnaphe and trnapro) and non-coding sequence, mitochondrial displacement loop (mtdna d-loop), in the cancerous and non-cancerous lesions of iranian patients with breast cancer (bc). genomic dna was extracte...

Backgrounds: Evidence is accumulating to support disruption of tissue architecture as a powerful event in tumor formation. For the past four decades, intensive cancer research with the premise of “cancer as a cell based-disease” focused on finding oncogenes or tumor suppressor genes. However, the role of the tissue architecture was neglected. Three dimensional (3D) cell cultures which can recap...

pancreatic cancer (pc) is a progressive, fatal disease with a high degree of malignancy. more than 40000 peoplediefrom this cancer annually in the united states. as a multifactorial condition, pc has a complex nature, and there are several genes and signalingpathwaysimplicated in pc pathogenesis and progression. there are diffèrent mutations in master genesincludingtumorsuppressors and oncogene...