Author details Orphan Medicines Office, European Medicines Agency, 7 Westferry Circus, Canary Wharf, London E144HB, UK. Bundesinstitut für Arzneimittel und Medizinprodukte, Kurt-Georg-Kiesinger-Allee 3, Bonn 53175, Germany. Läkemedelsverket, Dag Hammarskjölds vägen 42, Uppsala 75103, Sweden. Research Institute for Medicines (iMED.ULisboa), Faculty of Pharmacy, University of Lisbon, Lisboa 1649-...

Macrolophus pygmaeus (Rambur) (Hemiptera: Miridae) is widely distributed throughout the Palaearctic region. The aim was to explain the current geographic distribution of the species by investigating its genetic population structure. Samples of M. pygmaeus were collected in 15 localities through its range of distribution. A sample from a commercial producer was also analyzed. A total of 367 M. p...

Tolpis consists of ∼13 species native to Africa, Europe, and Macaronesia, with at least one species endemic to each of the four major archipelagos of the Azores, Madeira Islands, Canary Islands, and Cape Verde Islands. All but two of these species develop woody stems by maturity. Chloroplast DNA restriction site variation was analyzed for all species of Tolpis and four outgroups in order to und...

Abstract In 2014 the Island of El Hierro (Canary Islands) was declared a Geopark Unesco network, thus becoming first UNESCO geopark Canary Islands. The geological history can be understood through visit 61 geosites, which are representative growth and destruction an oceanic in intraplate environment. heritage represented by these geosites has as foremost exponents those related to formation meg...

Bird songs range in form from the simple notes of a Chipping Sparrow to the rich performance of the nightingale. Non-adjacent correlations can be found in the syntax of some birdsongs, indicating that the choice of what to sing next is determined not only by the current syllable, but also by previous syllables sung. Here we examine the song of the domesticated canary, a complex singer whose son...

A spokesm an for the Dutch airline KLM said all 235 p assen ­ gers and 14 crew m em bers aboard its Boeing 747 w ere killed w hen it collided with a Pan A m erican Boeing 747. Pan American officials in London said the ir plane was carrying 380 passengers and 16 crew m en. In Los A ngeles, w here the Pan American flight originated, officials said the plane had 370 passengers. A irport officials ...

1. Kelly PJ, Beati L, Matthewman LA, Mason PR, Dasch GA, Raoult D. A new pathogenic spotted fever group rickettsia from Africa. J Trop Med Hyg. 1994;97:129–37. 2. Raoult D, Fournier PE, Fenollar F, Jensenius M, Prioe T, de Pina JJ, et al. Rickettsia africae, a tick-borne pathogen in travelers to sub-Saharan Africa. N Engl J Med. 2001;344:1504–10. DOI: 10.1056/ NEJM200105173442003 3. Ndip LM, Bo...