Background: Calotropis gigantea (family: Asclepiadaceae) has been known to contain cardiac glycosides. The C. gigantea extracts have been reported as cytotoxic to a few cancer cell lines. The present study was designed to examine the effect of Calotropis gigantea methanolic extract (CGME) on the growth and apoptosis in human breast carcinoma cell line (MCF-7 cells).Methods: The study was ...

The protective effect of Calotropis gigantea flower extract in acute alcohol induced hepatotoxicity in rats was evaluated. A significant increase in the levels of enzyme markers of tissues damage (ALT, AST and ALP), lipid peroxidation (TBARS) and decreased serum vitamin C levels were observed in alcohol intoxicated rats as compared to control animals. Pretreatment with 250 and 500 mg/kg body we...

Calotropis procera, is known as crown flower or giant milkweed and belongs to the family Asclepiadacea. It has been traditionally used for various medicinal purposes. In present study, phytochemical analysis, antioxidant property, antimicrobial activity of C. procera were evaluated. Methanol was a solvent extract preparation using soxhlet extraction. The extracts subjected analysis different se...