نتایج جستجو برای: calorie restriction diet

تعداد نتایج: 230513  

2016
Matthew J. White Charlotte M. Beaver Martin R. Goodier Christian Bottomley Carolyn M. Nielsen Asia-Sophia F. M. Wolf Luisa Boldrin Charlotte Whitmore Jennifer Morgan Daniel J. Pearce Eleanor M. Riley

Immune senescence is a natural consequence of aging and may contribute to frailty and loss of homeostasis in later life. Calorie restriction increases healthy life-span in C57BL/6J (but not DBA/2J) mice, but whether this is related to preservation of immune function, and how it interacts with aging, is unclear. We compared phenotypic and functional characteristics of natural killer (NK) cells a...

2018
Osamu Kusuoka Rina Fujiwara-Tani Chie Nakashima Kiyomu Fujii Hitoshi Ohmori Takuya Mori Shingo Kishi Yoshihiro Miyagawa Kei Goto Isao Kawahara Hiroki Kuniyasu

The effect of intermittent calorie restriction (ICR) on cancer is controversial. In this study, we examined the effects of ICR and food content in syngeneic BALB/c mice injected with CT26 mouse colon cancer cells. Mice were subjected to 24-h fasting once a week for 4 weeks, and then provided with a control, high-calorie, or trans fatty acid-rich diet. While ICR resulted in increases in tumor we...

Journal: :Cancer prevention research 2011
Olga P Rogozina Melissa J L Bonorden Christine N Seppanen Joseph P Grande Margot P Cleary

The effect of chronic (CCR) and intermittent (ICR) caloric restriction on serum adiponectin and leptin levels was investigated in relation to mammary tumorigenesis. 10-wks old MMTV-TGF-α female mice were assigned to ad libitum fed (AL; AIN-93M diet), ICR (3-week 50% caloric restriction, AIN-93M-mod diet, 2× protein, fat, vitamins, and minerals followed by 3-wks 100% AL consumption of AIN-93M), ...

2013
Yuji Ikeno Gene B. Hubbard Shuko Lee Sara M. Dube Lisa C. Flores Madeline G. Roman Andrzej Bartke

Since 1996, aging studies using several strains of long-lived mutant mice have been conducted. Among these studies, Ames dwarf mice have been extensively examined to seek clues regarding the role of the growth hormone/insulin-like growth factor-1 axis in the aging process. Interestingly, these projects demonstrate that Ames dwarf mice have physiological characteristics that are similar to those...

2015
David Lusseau Sharon E. Mitchell Ceres Barros Davina Derous Cara Green Luonan Chen Jing-Dong Jackie Han Yingchun Wang Daniel E. L. Promislow Alex Douglas John R. Speakman

Animals have to adjust their activities when faced with caloric restriction (CR) to deal with reduced energy intake. If CR is pronounced, allostasis can push individuals into alternate physiological states which can result in important health benefits across a wide range of taxa. Here we developed a new approach to determine the changes in behavioural phenotype associated with different levels ...

Journal: :International journal of cancer management 2021

Context: Somatic mutation theory has been considered as a potential cause for cancer. However, major inconsistencies with the gene have necessitated serious reconsideration of this assumption. According to these inconsistencies, cancer may be metabolic disorder. mitochondrial theory, substrate-level phosphorylation suggested superior oxidative in cells. Cancer therapies such ketogenic diets (KD...

Journal: :Journal of Education, Health and Sport 2023

Introduction: Cardiovascular diseases (CVDs) remain major problem in modern medicine. According to World Health Organization they are the leading cause of death. Despite increased awareness about impact healthy lifestyle, mortality still remains on high level. requires multidisciplinary treatment. One those aspects is determinate an appropriate diet. Purpose: The aim this systemic review collec...

2017
Shuang E Kazushi Yamamoto Yu Sakamoto Yui Mizowaki Yui Iwagaki Toshiyuki Kimura Kiyotaka Nakagawa Teruo Miyazawa Tsuyoshi Tsuduki

The effect of 1-deoxynojirimycin, a caloric restriction mimetic, was examined in ICR mice with azoxymethane dextran sodium sulfate-induced colorectal cancer. Azoxymethane is a carcinogen (10 mg/kg body weight), and 2% dextran sodium sulfate (w/v) used as a colitis-inducing agent. Mice were separated into 5 groups: a group without colorectal cancer fed a normal diet (CO- group), and groups with ...

Journal: :Obesity 2007
Corby K Martin Leonie K Heilbronn Lilian de Jonge James P DeLany Julia Volaufova Stephen D Anton Leanne M Redman Steven R Smith Eric Ravussin

OBJECTIVE It is unclear if resting metabolic rate (RMR) and spontaneous physical activity (SPA) decrease in weight-reduced non-obese participants. Additionally, it is unknown if changes in SPA, measured in a respiratory chamber, reflect changes in free-living physical activity level (PAL). RESEARCH METHODS AND PROCEDURES Participants (N = 48) were randomized into 4 groups for 6 months: calori...

Journal: :Chronobiology international 2005
Fernando Chacón Ana I Esquifino Mario Perelló Daniel P Cardinali Eduardo Spinedi María P Alvarez

Calorie restriction of young male rats increases plasma prolactin, decreases luteinizing hormone (LH) and testosterone, and disrupts their 24 h secretory pattern. To study whether this could be the consequence of stress, we examined the 24 h variations of plasma adrenocorticotropic hormone (ACTH) corticosterone, growth hormone (GH), leptin, and adrenal corticosterone. Rats were submitted to a c...

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