Abstract Exposure to endocrine disrupting chemicals is an important public health concern although only a few disruption have been identified so far. To speed up their identification, in silico toxicological models appear be the most appropriate, since potential of large number compounds can estimated short time. In this study three (Endocrine disruptome software, VirtualToxLab and COSMOS KNIME...

Chemicals identified as endocrine-disrupting compounds (EDCs) have widespread consumer uses, yet little is known about indoor exposure. We sampled indoor air and dust in 120 homes, analyzing for 89 organic chemicals identified as EDCs. Fifty-two compounds were detected in air and 66 were detected in dust. These are the first reported measures in residential environments for over 30 of the compo...

Many chemicals which are released into the environment have the potential to disrupt the function of endocrine systems. They pose a growing threat to human and wildlife health. These chemicals have been characterized as endocrine disrupting chemicals. Some phenolic chemicals, such as bisphenol A, have been measured in surface water, sediments and sewage sludge. The objective of this study was t...

Human semen quality is declining in many parts of the world, but the causes are ill defined. In rodents, impaired sperm production can be seen with early life exposure to certain endocrine-disrupting chemicals, but the effects of combined exposures are not properly investigated. In this study, we examined the effects of early exposure to the painkiller paracetamol and mixtures of human relevant...

Civilization, industrialization, and urbanization create an environment where humans are continuously exposed to endocrine disrupting chemicals (EDCs). Some of breast cancers and endometrial cancer, which are the most common female malignant neoplasms, are estrogen-dependent tumors. Prolonged exposure to estrogens or substances with estrogenic properties may be a risk factor for their developme...