نتایج جستجو برای: cacs
تعداد نتایج: 416 فیلتر نتایج به سال:
BACKGROUND Coronary artery disease (CAD) is a major cardiovascular complication in diabetic patients. Despite the significant association between obesity and diabetes, the majority of the diabetic subjects are not obese in an Asian population. This study evaluated the association between obesity and coronary artery disease (CAD) according to the diabetes status in a Korean population. METHODS...
BACKGROUND The structure of the aorta is considered to influence exercise systolic blood pressure (SBP) response, which, in turn, might impact upon adverse outcomes. The current study sought to investigate the relationship of aortic calcification and exercise SBP with adverse outcomes among elderly individuals. METHODS AND RESULTS We retrospectively reviewed 702 elderly individuals (>65 years...
The purpose of this study was to find the circulating microRNAs (miRNAs) co-related with the severity of coronary artery calcification (CAC), and testify whether the selected miRNAs could reflect the obstructive coronary artery disease in symptomatic patients. Patients with chest pain and moderated risk for coronary artery disease (CAD) were characterized with coronary artery calcium score (CAC...
BACKGROUND Circulating angiogenic cytokines (CACs) have been confirmed as prognostic biomarkers and therapeutic targets in several solid tumors. However, their role as prognostic biomarkers in resected pancreatic ductal adenocarcinoma (PDAC) is unknown. RESULTS The expression of CACs in patients with PDAC differs from those with CP both pre- and postoperatively. Correlation analyses show sign...
The Notch-signaling pathway is known to be fundamental in controlling pancreas differentiation. We now report on using Cre-based fate mapping to indelibly label pancreatic Notch-responsive cells (PNCs) at larval stages and follow their fate in the adult pancreas. We show that the PNCs represent a population of progenitors that can differentiate to multiple lineages, including adult ductal cells...
BACKGROUND Patients suffering from ulcerative colitis (UC) bear an increased risk for colorectal cancer. Due to the sparsity of colitis-associated cancer (CAC) and the long duration between UC initiation and overt carcinoma, elucidating mechanisms of inflammation-associated carcinogenesis in the gut is particularly challenging. Adequate murine models are thus highly desirable. For human CACs a ...
BACKGROUND Coronary artery calcium score (CACS) is a quantitative assessment of calcifications and an established predictor of cardiovascular events. OBJECTIVES In this study, we evaluated the diagnostic accuracy, negative predictive value (NPV), positive predictive value (PPV), specificity and sensitivity of CACS less than 100 in predicting significant coronary artery stenosis in patients wi...
A high coronary artery calcification score (CACS) may be associated with mortality in patients undergoing hemodialysis (HD). Recently, effects of iron on vascular smooth muscle cell calcificat...
Abstract Background Recently, the European Society of Cardiology issued new algorithms to estimate 10-year risk atherosclerotic cardiovascular disease (ASCVD), along with age-specific thresholds classify individuals as low-to-moderate, high, or very-high risk. The aim this study was compare latest SCORE-2 model older SCORE (Systematic COronary Risk Evaluation) in their ability identify high cor...
BackgroundWhether coronary plaque characteristics assessed in computed tomography angiography (CCTA) association with the artery calcium score (CACS) have predictive value for events is unclear. We aimed to examine of CACS and occurrence events.MethodsAmong 2802 patients who were analyzed PREDICT registry, 2083 suspected disease (CAD) studied using post hoc analysis. High-risk plaques defined a...
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