نتایج جستجو برای: c57bl6

تعداد نتایج: 1088  

2017
Jashdeep Bhattacharjee Michelle Kirby Samir Softic Lili Miles Rosa‐Maria Salazar‐Gonzalez Pranav Shivakumar Rohit Kohli

Hepatic inflammation is a key pathological feature of Nonalcoholic Steatohepatitis (NASH). Natural Killer T-cells (NKT) and CD8+ T-cells are known to play an important role in obesity related adipose tissue inflammation. We hypothesized that these same inflammatory phenotypes would be present in progressive NASH. We used a previously established high fat high carbohydrate (HFHC) murine obesogen...

Journal: :Journal of Investigative Dermatology 2023

Mucous membrane pemphigoid (MMP) is an autoimmune blistering disease that most frequently affects the oral cavity and conjunctivae. Additional skin lesions may appear in about a quarter of patients. The current therapeutic armamentarium mainly based on long-term immunosuppression, which associated with high number adverse events not effective. Here, we investigated effects topical conjunctival ...

Journal: :Cancers 2023

NB, being a highly metastatic cancer, is one of the leading causes cancer-related deaths in children. Increased disease recurrence and clinical resistance patients with high-risk NBs (HR-NBs) result poor outcomes lower overall survival. However, paucity appropriate vivo models for HR-NB metastasis has limited investigations into underlying biology metastasis. This study was designed to address ...

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