Streptomyces sp. strain C34, isolated from soil collected in the Chilean hyper-arid Atacama Desert, was cultured on different media, resulting in the isolation and identification of four new ansamycin-type polyketides. The organism was selected for chemical investigation on the basis of a genome-mining PCR-based experiment targeting the gene encoding rifamycin-specific 3-amino-5-hydroxybenzoic ...

______________________________________________________________________________ This study analyses the characteristics of both recipients and givers of private transfers from a sample of Australian migrants. It utilises a unique longitudinal household survey conducted on immigrants entering Australia with permanent residency. Sample selection bias that arises from the limited observations that ...

OBJECTIVES To identify the effects of supplemental private health insurance on health care utilization and expenditure under the mandatory National Health Insurance(NHI) system in Korea. METHODS The data were collected by the National Cancer Center in Korea. Cancer patients who were newly diagnosed with stomach (ICD code, C16), lung(C33-C34), liver (C22), colorectal cancer(C18-C20) or breast(...

Earlier we reported on the presence of a specific phenolic glycolipid (Phenolic Glycolipid-I) in Mycobacterium leprae, and in infected armadillo tissues (Hunter, S. W., and Brennan, P. J. (1981) J. Bacteriol. 147, 728-735). It had an inherent oligosaccharide, composed of 3-O-Me-rhamnose, 2,3-di-O-Me-rhamnose, and 3,6-di-O-Me-glucose, glycosidically linked to the phenol substituent. The structur...

Health state utility data generated using the EQ-5D instrument are typically right bounded at one with a substantial gap to the next set of observations, left bounded by some negative value, and are multi modal. These features present challenges to the estimation of the e¤ect of clinical and socioeconomic characteristics on health utilities. We present an adjusted censored model and then use th...

Surface sediments were collected from various locations of the Mandovi estuary and the Marmugoa harbour. Sediments were analysed for organic carbon (OC), total lipids, n-alkanes concentration and composition. Concentrations of OC, total lipids and n-alkanes varied spatially and ranged from 1 to 2.5%, 176 to 1413 microg/g dry weight (dw) sediments, and 0.8 to 3.2 microg/g dw sediments of the Man...

The molecular interactions between valyl-tRNA synthetase (ValRS) and tRNA(Val), with the C34-A35-C36 anticodon, from Thermus thermophilus were studied by crystallographic analysis and structure-based mutagenesis. In the ValRS-bound structure of tRNA(Val), the successive A35-C36 residues (the major identity elements) of tRNA(Val) are base-stacked upon each other, and fit into a pocket on the alp...

abstract background: lung cancer is an important cause of cancer mortality. mortality is a familiar projection to address the burden of cancers. however, according to iranian death registry, about 20% of death statistics were still recorded in misclassified categories. the aim of this study was to estimate lung cancer mortality in iranian population, using bayesian approach to revise this miscl...

In the phase III ALEX study, alectinib demonstrated superior progression-free survival over crizotinib for treatment-naïve patients with ALK+ NSCLC. This study aims to evaluate health resource utilization (HRU) and costs receiving or as first ALK inhibitor (ALKi). retrospective observational identified ≥ 18 years old lung cancer (ICD-9: 162, ICD-10: C34) their ALKi between 1/1/2015 6/30/2019 fr...

published in Aduance ACS Abstracts, February 15, 1994. 0095-233819411634-0421$04.50/0 Fueled by the intense activity in fullerene chemistry and intrinsically interesting geometrical and topological features of fullerenes, several studies have focused on the fascinating mathematical properties of fullerenes. These studies included graph theoretical computations of the characteristic polynomials,...