نتایج جستجو برای: c receptors

تعداد نتایج: 1249573  

Journal: :modares journal of medical sciences: pathobiology 2009
oghol niaz jorjani fatemeh ghaffarifar zohreh sharifi abdolhossein dalimi zahir mohammad hassan

objective: leishmaniasis is caused by parasitic protozoa of the genus leishmania which in the infected host is obligate intracellular parasite. lack gene is conserved among related leishmania species. lack is the immuno-dominant antigen of l.major which is considered as the most promising molecule for a recombinant or dna vaccine against leishmaniasis. materials and methods: in this study the ...

2012
Zhen-Ying Cheng Mary Chebib Katrina L. Schmid

PURPOSE The cornea has an important role in vision, is highly innervated and many neurotransmitter receptors are present, e.g., muscarine, melatonin, and dopamine receptors. γ-aminobutyric acid (GABA) is the most important inhibitory neurotransmitter in the retina and central nervous system, but it is unknown whether GABA receptors are present in cornea. The aim of this study was to determine i...

Journal: :iranian journal of pharmaceutical research 0
fatemeh ahmadi department of radiopharmacy, school of pharmacy, tehran university of medical sciences sara dabirian department of pharmaceutical chemistry, school of pharmacy, shahid behesti university of medical sciences mehrdad faizi department of pharmacology and toxicology, school of pharmacy, shahid beheshti university of medical sciences sayyed abbas tabatabai department of pharmaceutical chemistry, school of pharmacy, shahid behesti university of medical sciences davood beiki research center for nuclear medicine, tehran university of medical sciences soraya shahhosseini department of pharmaceutical chemistry, school of pharmacy, shahid beheshti university of medical sciences

to obtain drugs which are more selective at benzodiazepine (bzd) receptors, design and synthesis of functionally selective ligands for bzd receptors is the current strategy of our pharmaceutical chemistry department. the affinity of newly synthesized ligands is assessed by radioligand receptor binding assays. based on our previous studies, 2-phenyl-5-oxo-7-methyl-1,3,4-oxadiazolo[a,2,3]-pyrimid...

Journal: :The Journal of Experimental Medicine 1975
G D Ross M J Polley

Erythrocytes, bone marrow-derived lymphocytes, monocytes, and granulocytes were shown to have a receptor activity for C4. Theis C4 receptor activity was studied in relation to the previously identified C3b and C3d receptors. By assay for inhibition of rosette formation by fluid-phase complement (C), only two different lymphocyte C receptors were demonstrated. The immune adherence receptor, the ...

Journal: :Proteins 2021

In vertebrates, the mineralocorticoid receptor (MR) is a steroid-activated nuclear (NR) that plays essential roles in water-electrolyte balance and blood pressure homeostasis. It belongs to group of oxo-steroidian NRs, together with glucocorticoid (GR), progesterone (PR), androgen (AR) receptors. Classically, these NRs homodimerize bind specific genomic sequences activate gene expression. are m...

To obtain drugs which are more selective at benzodiazepine (BZD) receptors, design and synthesis of functionally selective ligands for BZD receptors is the current strategy of our pharmaceutical chemistry department. The affinity of newly synthesized ligands is assessed by radioligand receptor binding assays. Based on our previous studies, 2-phenyl-5-oxo-7-methyl-1,3,4-oxadiazolo[a,2,3]-pyrimid...

2001
Cary P. Moxham

6,and b2-adrenergic receptors, pharmacologically distinct proteins, have been reported to be structurally dissimilar. In the present study three techniques were employed to compare the nature of mammalian &and Bz-adrenergic receptors. Antibodies against each of the receptor subtypes were raised separately. Polyclonal antisera against &-receptors f rat fat cells were raised in mice, and antisera...

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